UniProt Accession

 HSBP1_RAT; Q8K3X8 

Genbank Protein ID

 AF522937; BC058131 

Genbank Nucleotide ID

 AAM81322.1; AAH58131.1 

Protein Name

 Heat shock factor-binding protein 1 

Protein Synonyms/Alias

  

Gene Name

 Hsbp1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
75	NKIPTAQKS******	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Negative regulator of the heat shock response. Negatively affects HSF1 DNA-binding activity. May have a role in the suppression of the activation of the stress response during the aging process (By similarity). 

Sequence Annotation

  

Keyword

 Complete proteome; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 76 AA 

Protein Sequence

Gene Ontology

 GO:0005856; C:cytoskeleton; IDA:RGD.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0006936; P:muscle contraction; IDA:RGD. 

Interpro

 IPR009643; HS1-bd. 

Pfam

 PF06825; HSBP1 

SMART

  

PROSITE

  

PRINTS