CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006586
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ribosomal RNA-processing protein 14 
Protein Synonyms/Alias
 Ribosome biogenesis protein RRP14 
Gene Name
 RRP14 
Gene Synonyms/Alias
 YKL082C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
54SKNDKLKKLDPEQRDacetylation[1]
87PVVLPGEKFKHMKMQacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
 Involved in ribosome biogenesis and cell polarity. Required for the synthesis of both 40S and 60S ribosomal subunits and may also play some direct role in correct positioning of the mitotic spindle during mitosis. 
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Nucleus; Reference proteome; Ribosome biogenesis; rRNA processing. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 434 AA 
Protein Sequence
MSNSLEERLR ANSSAFDGLL ALIPAKYYYD EKSQEQWKAK KKTKEQSKND KLKKLDPEQR 60
DDETSSTLEV MKKKEKDAKP VVLPGEKFKH MKMQKQKEAT SKVEGDSDLN VEVNDPMIIA 120
PDEDEEEEED IKVIFDDEGN EIPLESKKDT TEPDRSVEKK SITEEEKLQR KKNLEALRSK 180
LQAKISDMKS KRKAPGSREA ILAQRKRKEE LKKRKRLESE QEQDQDEIAS DSDMEDIDSD 240
LENNSKKRFK KGKKDSEINA DGVMFQNIIF DDGARATSDL QRLRKAGRTK GPAKNDVKSH 300
LKLLEAKKNK MEAKDELEQI KQKEKEKWQK AMLQAEGIKI RDDEKLLRKA IKRKEAQKRK 360
SAIEWSERKR VVEDTISERQ KRREENLRIR KDNKGKKRNK QEKMKRKYVG SAVPKKRAGF 420
EGRLKTGKKK GGPK 434 
Gene Ontology
 GO:0005730; C:nucleolus; IDA:SGD.
 GO:0042273; P:ribosomal large subunit biogenesis; IMP:SGD.
 GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.
 GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. 
Interpro
 IPR007019; Surf6. 
Pfam
 PF04935; SURF6 
SMART
  
PROSITE
  
PRINTS