UniProt Accession

 F5H7Q8_HUMAN; F5H7Q8 

Genbank Protein ID

 AL663061 

Genbank Nucleotide ID

  

Protein Name

 MHC class I polypeptide-related sequence B 

Protein Synonyms/Alias

  

Gene Name

 MICB 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
35	DRQKRRAKPQGQWAE	ubiquitination	[1]
72	RRTLTHIKDQKGGLH	ubiquitination	[1]
75	LTHIKDQKGGLHSLQ	ubiquitination	[1, 2]
138	MNVTNFWKEDAMKTK	ubiquitination	[1]
158	MQADCLQKLQRYLKS	ubiquitination	[1]
164	QKLQRYLKSGVAIRR	ubiquitination	[1]
267	THPVPSGKALVLQSQ	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 351 AA 

Protein Sequence

Gene Ontology

 GO:0042612; C:MHC class I protein complex; IEA:InterPro.
 GO:0019882; P:antigen processing and presentation; IEA:InterPro.
 GO:0006955; P:immune response; IEA:InterPro. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2. 

Pfam

 PF07654; C1-set
 PF00129; MHC_I 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE 

PRINTS