UniProt Accession

 H0Y9P9_HUMAN; H0Y9P9 

Genbank Protein ID

 AC064824; AC069200 

Genbank Nucleotide ID

  

Protein Name

 Polyprenol reductase 

Protein Synonyms/Alias

  

Gene Name

 SRD5A3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
31	LIRYGKTKCGEPSRP	ubiquitination	[1]
48	CRAFDVPKRYFSHFY	ubiquitination	[2]
166	SHQFYKSKFVSYPKH	ubiquitination	[1]
175	VSYPKHRKAFLPFLF	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
 GO:0006629; P:lipid metabolic process; IEA:InterPro. 

Interpro

 IPR001104; 3-oxo-5_a-steroid_4-DH_C. 

Pfam

 PF02544; Steroid_dh 

SMART

  

PROSITE

 PS50244; S5A_REDUCTASE 

PRINTS