CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041141
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Serine/threonine-protein kinase BRSK2 
Protein Synonyms/Alias
  
Gene Name
 Brsk2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
28RLEKTLGKGQTGLVKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 697 AA 
Protein Sequence
MTSTGKDGGG AQHAQYVGPY RLEKTLGKGQ TGLVKLGIHC VTCQKVAIKI VNREKLSESV 60
LMKVEREIAI LKLIEHPHVL KLHDVYENKK YLYLVLEHVS GGELFDYLVK KGRLTPKEAR 120
KFFRQIISAL DFCHSHSICH RDLKPENLLL DERNNIRIAD FGMASLQVGD SLLETSCGSP 180
HYACPEVIRG EKYDGRKADV WSCGVILFAL LVGALPFDDD NLRQLLEKVK RGVFHMPHFI 240
PPDCQSLLRG MIEVDAARRL TLEHIQKHIW YIGGKNEPEP EQPIPRKVQI RSLPSLEDID 300
PDVLDSMHSL GCFRDRNKLL QDLLSEEENQ EKMIYFLLLD RKERYPSHED EDLPPRNEID 360
PPRKRVDSPM LNRHGKRRPE RKSMEVLSVT DGGSPVPARR AIEMAQHGQS KAVFSKSLDI 420
AEAHPQFSKE DRSRSISGAS SGLSTSPLSS PRVTPHPSPR GSPLPTPKGT PVHTPKESPA 480
GTPNPTPPSS PSVGGVPWRT RLNSIKNSFL GSPRFHRRKL QVPTPEEMSN LTPESSPELA 540
KKSWFGNFIN LEKEEQIFVV IKDKPLSSIK ADIVHAFLSI PSLSHSVISQ TSFRAEYKAT 600
GGPAVFQKPV KFQVDITYTE GGEAQKENGI YSVTFTLLSG PSRRFKRVVE TIQAQLLSTH 660
DQPSAQHLSE PPPPAPGLSW GAGLKGQKVA TSYESSL 697 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
 GO:0030010; P:establishment of cell polarity; IGI:MGI.
 GO:0048812; P:neuron projection morphogenesis; IGI:MGI.
 GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR017441; Protein_kinase_ATP_BS.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS00107; PROTEIN_KINASE_ATP
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS