| Tag | Content |
|---|
| CPLM ID | CPLM-003714 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
Protein Synonyms/Alias | D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine--D-fructose-6-phosphate amidotransferase |
Gene Name | glmS |
Gene Synonyms/Alias | gcaA; ybxD; BSU01780 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 446 | MEALCDQKDEMEMIA | acetylation | [1] | | 483 | VEGALKLKEISYIQA | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity). |
Sequence Annotation | DOMAIN 2 217 Glutamine amidotransferase type-2.
DOMAIN 283 422 SIS 1.
DOMAIN 452 590 SIS 2.
ACT_SITE 2 2 Nucleophile; for GATase activity (By
ACT_SITE 595 595 For Fru-6P isomerization activity (By |
Keyword | Aminotransferase; Complete proteome; Cytoplasm; Glutamine amidotransferase; Reference proteome; Repeat; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 600 AA |
Protein Sequence | MCGIVGYIGQ LDAKEILLKG LEKLEYRGYD SAGIAVANEQ GIHVFKEKGR IADLREVVDA 60
NVEAKAGIGH TRWATHGEPS YLNAHPHQSA LGRFTLVHNG VIENYVQLKQ EYLQDVELKS 120
DTDTEVVVQV IEQFVNGGLE TEEAFRKTLT LLKGSYAIAL FDNDNRETIF VAKNKSPLLV 180
GLGDTFNVVA SDAMAMLQVT NEYVELMDKE MVIVTDDQVV IKNLDGDVIT RASYIAELDA 240
SDIEKGTYPH YMLKETDEQP VVMRKIIQTY QDENGKLSVP GDIAAAVAEA DRIYIIGCGT 300
SYHAGLVGKQ YIEMWANVPV EVHVASEFSY NMPLLSKKPL FIFLSQSGET ADSRAVLVQV 360
KALGHKALTI TNVPGSTLSR EADYTLLLHA GPEIAVASTK AYTAQIAVLA VLASVAADKN 420
GINIGFDLVK ELGIAANAME ALCDQKDEME MIAREYLTVS RNAFFIGRGL DYFVCVEGAL 480
KLKEISYIQA EGFAGGELKH GTIALIEQGT PVFALATQEH VNLSIRGNVK EVAARGANTC 540
IISLKGLDDA DDRFVLPEVN PALAPLVSVV PLQLIAYYAA LHRGCDVDKP RNLAKSVTVE 600 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:HAMAP. GO:0016051; P:carbohydrate biosynthetic process; IEA:InterPro. GO:0006541; P:glutamine metabolic process; IEA:HAMAP. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |