| Tag | Content |
|---|
| CPLM ID | CPLM-011821 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NuA3 HAT complex component NTO1 |
Protein Synonyms/Alias | |
Gene Name | NTO1 |
Gene Synonyms/Alias | YPR031W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 125 | SRYYHINKVRNRKSY | acetylation | [1] | | 580 | KELTTLVKKRTQASN | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Component of the NuA3 histone acetyltransferase complex, that acetylates Lys-14 of histone H3. Recruitment of NuA3 to nucleosomes requires methylated histone H3. In conjunction with the FACT complex, NuA3 may be involved in transcriptional regulation. |
Sequence Annotation | ZN_FING 263 313 PHD-type.
MOD_RES 728 728 Phosphoserine. |
Keyword | Complete proteome; Cytoplasm; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 748 AA |
Protein Sequence | MNRGSLDDGP KLREEKHFQD FYPDLNADTL LPFIVPLVET KDNSTDTDSD DISNRNNREI 60
GSVKSVQTKE LIFKGRVTTE PLVLKKNEVE FQKCKITTNE LKGKKNPYCV RFNESFISRY 120
YHINKVRNRK SYKQQQKEFD GVEAPYFTKF SSKEAPNITI STSTKSAIQK FASISPNLVN 180
FKPQYDMDEQ DELYLHYLNK RYFKDQMSHE IFEILMTTLE TEWFHIEKHI PSTNSLIARH 240
NILRDCKNYE LYGSDDGTGL SMDQACAVCL GTDSDNLNTI VFCDGCDIAV HQECYGIIFI 300
PEGKWLCRRC MISKNNFATC LMCPSHTGAF KQTDTGSWVH NICALWLPEL YFSNLHYMEP 360
IEGVQNVSVS RWKLNCYICK KKMGACIQCF QRNCFTAYHV TCARRAGLYM SKGKCTIQEL 420
ASNQFSQKYS VESFCHKHAP RGWQTSIEGI NKARKYFSLL STLQTETPQH NEANDRTNSK 480
FNKTIWKTPN QTPVAPHVFA EILQKVVDFF GLANPPAGAF DICKYWSMKR ELTGGTPLTA 540
CFENNSLGSL TEEQVQTRID FANDQLEDLY RLKELTTLVK KRTQASNSLS RSRKKVFDIV 600
KSPQKYLLKI NVLDIFIKSE QFKALERLVT EPKLLVILEK CKHCDFDTVQ IFKEEIMHFF 660
EVLETLPGAS RILQTVSSKA KEQVTNLIGL IEHVDIKKLL SRDFIINDDK IEERPWSGPV 720
IMEEEGLSDA EELSAGEHRM LKLILNSG 748 |
Gene Ontology | GO:0005737; C:cytoplasm; IDA:SGD. GO:0033100; C:NuA3 histone acetyltransferase complex; IDA:SGD. GO:0004402; F:histone acetyltransferase activity; IPI:SGD. GO:0035064; F:methylated histone residue binding; IDA:SGD. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |