UniProt Accession

 DPM1_PIG; A5GFZ5 

Genbank Protein ID

 CR974565; CT009560; CT009560; CR974565 

Genbank Nucleotide ID

 CAN13124.1; CAN13124.1; CAN13232.1; CAN13232.1 

Protein Name

 Dolichol-phosphate mannosyltransferase 

Protein Synonyms/Alias

 Dolichol-phosphate mannose synthase; DPM synthase; Dolichyl-phosphate beta-D-mannosyltransferase; Mannose-P-dolichol synthase; MPD synthase 

Gene Name

 DPM1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Sus scrofa (Pig) 

NCBI Taxa ID

 9823 

Lysine Modification

Position	Peptide	Type	References
133	FIPEFIRKQKEGNFD	ubiquitination	[1]
239	DRVYGESKLGGNEIV	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins (By similarity). 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Complete proteome; Endoplasmic reticulum; Glycosyltransferase; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 259 AA 

Protein Sequence

Gene Ontology

 GO:0033185; C:dolichol-phosphate-mannose synthase complex; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.
 GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; ISS:UniProtKB.
 GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; ISS:UniProtKB.
 GO:0019348; P:dolichol metabolic process; IEA:Compara.
 GO:0006506; P:GPI anchor biosynthetic process; ISS:UniProtKB.
 GO:0035269; P:protein O-linked mannosylation; ISS:UniProtKB. 

Interpro

 IPR001173; Glyco_trans_2. 

Pfam

 PF00535; Glycos_transf_2 

SMART

  

PROSITE

  

PRINTS