UniProt Accession

 EMC4_HUMAN; Q5J8M3; A8K3A9; B4DJQ4; Q96KX9; Q9BUI5; Q9P0T9 

Genbank Protein ID

 AY336092; AF151018; AK075227; AK290524; AK296184; AC079203; CH471125; BC002583 

Genbank Nucleotide ID

 AAR24622.1; AAF36104.1; BAC11486.1; BAF83213.1; BAG58916.1; EAW92292.1; AAH02583.1 

Protein Name

 ER membrane protein complex subunit 4 

Protein Synonyms/Alias

 Cell proliferation-inducing gene 17 protein; Transmembrane protein 85 

Gene Name

 EMC4 

Gene Synonyms/Alias

 TMEM85; HSPC184; PIG17 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
50	YPVGYLDKQVPDTSV	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 May mediate anti-apoptotic activity. 

Sequence Annotation

  

Keyword

 Alternative splicing; Apoptosis; Complete proteome; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 183 AA 

Protein Sequence

Gene Ontology

 GO:0072546; C:ER membrane protein complex; IDA:UniProtKB.
 GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. 

Interpro

 IPR009445; DUF1077_TMEM85. 

Pfam

 PF06417; DUF1077 

SMART

  

PROSITE

  

PRINTS