| Tag | Content |
|---|
| CPLM ID | CPLM-018675 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transmembrane protein 132A |
Protein Synonyms/Alias | HSPA5-binding protein 1 |
Gene Name | Tmem132a |
Gene Synonyms/Alias | Kiaa1583 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 872 | FVLRYQRKEPPDSAT | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May play a role in embryonic and postnatal development of the brain. Increased resistance to cell death induced by serum starvation in cultured cells. Regulates cAMP-induced GFAP gene expression via STAT3 phosphorylation (By similarity). |
Sequence Annotation | REGION 606 911 Binds to HSPA5/GRP78 (By similarity).
REGION 666 1018 Confers cellular localization similar to
CARBOHYD 276 276 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endoplasmic reticulum; Glycoprotein; Golgi apparatus; Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1018 AA |
Protein Sequence | MTERKAAAPR GPYGAWFCLL VALALEVVRV SSNHDTLDPI YLPVALELLD APEHFRVQQV 60
GHYPPANSSL ASRSETFLLM QPWPRAQPLL RASYPPFATQ QVVPPRVTEP HRRPVPWDVR 120
AVSVEAAVTP AEPYARVLFH LKGQDWPPGP GSLPCARLHA THPAGTAHRA CRFQPSLGAC 180
VVELQFPSHW FSQSATTRAE LAYTLEPAGE GPGGCGLGTE EEPREQALPV GGVELHPEDP 240
PQYQEVPLDE AVTLRAPDVP MRPGQLFTAT LLLRHNFTAS LLTLRIKVKK GLQVIAARPA 300
QPTLWTAKLD RFKGSKHHTS LITCHRAGPA GPDSSPLELS EFLWVDFAVE NSTGGGVAVT 360
RPVTWQLEYP GQAPEAEKDK MVWEILVSER DIRALIPLAK AEELVNTAPL TGVPQRIPVR 420
LVTVDSGGAL EEVTEHIGCE SANTQVLQVS EACDAVFVAG QESRGAKGVR VDFWWRRLRA 480
SLKLTVWAPL LPLRIELTDT TLEQIRGWRV PGSAEGQLEP ETAAEEVERR SRGCRLQYQR 540
AGVRFLVPFA AHPLDGGRRL THLLGPDWLL DVSHLVAAHA HVQDPRIASL EGGRILVGRE 600
PGVTSIEVRS PLSDAILGEQ ALAVTDDKVS VLDLRVQPVM GISLSLSRGM SHPGEVTATC 660
WAQSALPAPK QEVALSLWLS FSDHTLAPAE LYDRNDLGLS VSAEEPSAVL PAEEQGAQLG 720
VVVSGVGAEG LPLHVALHPP EPCRRGRHRV PLASGTAWLG LPPLPTPVPA LPSSPVRTSP 780
FTEATVEGKR QIAGDMGGHV GIRGKFERAE EEAGKEENEA KEEEEDEEEM VPAPQRVTDL 840
ELGMYALLGI FCLAILIFLV NGVVFVLRYQ RKEPPDSATD PASPQPHNWV WLGTNQEELS 900
RQLDRCSSSG PPKGEGGCPC ESGAGGDAST VAPSASESPA GSSSTLARKE AGGRRKRVEF 960
VTFAPAPPTQ PPEEPVGAPA VQSILVAGEE DIRWVCEDMG LKDPEELRNY MERIRGSS 1018 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |