CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004662
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADP,ATP carrier protein 2 
Protein Synonyms/Alias
 ADP/ATP translocase 2; Adenine nucleotide translocator 2; ANT 2; Petite colonies protein 9 
Gene Name
 PET9 
Gene Synonyms/Alias
 AAC2; YBL030C; YBL0421 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
48ASPIERVKLLIQNQDacetylation[1]
59QNQDEMLKQGTLDRKacetylation[1]
59QNQDEMLKQGTLDRKubiquitination[2]
75AGILDCFKRTATQEGacetylation[1]
182DVYKKTLKSDGVAGLacetylation[1]
286EGVGSLFKGCGANILacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. 
Sequence Annotation
 REPEAT 21 114 Solcar 1.
 REPEAT 125 217 Solcar 2.
 REPEAT 225 311 Solcar 3.
 MOTIF 252 257 Substrate recognition (By similarity).
 BINDING 96 96 Nucleotide (By similarity).  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 318 AA 
Protein Sequence
MSSNAQVKTP LPPAPAPKKE SNFLIDFLMG GVSAAVAKTA ASPIERVKLL IQNQDEMLKQ 60
GTLDRKYAGI LDCFKRTATQ EGVISFWRGN TANVIRYFPT QALNFAFKDK IKAMFGFKKE 120
EGYAKWFAGN LASGGAAGAL SLLFVYSLDY ARTRLAADSK SSKKGGARQF NGLIDVYKKT 180
LKSDGVAGLY RGFLPSVVGI VVYRGLYFGM YDSLKPLLLT GSLEGSFLAS FLLGWVVTTG 240
ASTCSYPLDT VRRRMMMTSG QAVKYDGAFD CLRKIVAAEG VGSLFKGCGA NILRGVAGAG 300
VISMYDQLQM ILFGKKFK 318 
Gene Ontology
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
 GO:0005471; F:ATP:ADP antiporter activity; IDA:SGD.
 GO:0015866; P:ADP transport; IDA:SGD.
 GO:0009060; P:aerobic respiration; IMP:SGD.
 GO:0009061; P:anaerobic respiration; IGI:SGD.
 GO:0006915; P:apoptotic process; IMP:SGD.
 GO:0015867; P:ATP transport; IDA:SGD.
 GO:0015886; P:heme transport; IMP:SGD.
 GO:0006839; P:mitochondrial transport; IMP:SGD. 
Interpro
 IPR002113; Aden_trnslctor.
 IPR002067; Mit_carrier.
 IPR018108; Mitochondrial_sb/sol_carrier.
 IPR023395; Mt_carrier_dom. 
Pfam
 PF00153; Mito_carr 
SMART
  
PROSITE
 PS50920; SOLCAR 
PRINTS
 PR00927; ADPTRNSLCASE.
 PR00926; MITOCARRIER.