CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025116
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor 3 subunit G 
Protein Synonyms/Alias
 eIF3g; Eukaryotic translation initiation factor 3 RNA-binding subunit; Eukaryotic translation initiation factor 3 subunit 4; eIF-3-delta; eIF3 p42; eIF3 p44 
Gene Name
 Eif3g 
Gene Synonyms/Alias
 Eif3s4 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
65EVINGNIKTVTEYKIubiquitination[1]
180DTLGPMQKELAEQLGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Component of the eukaryotic translation initiation factor 3 (eIF-3) complex (By similarity). 
Sequence Annotation
 DOMAIN 239 317 RRM (By similarity).
 MOD_RES 41 41 Phosphothreonine (By similarity).
 MOD_RES 42 42 Phosphoserine (By similarity).  
Keyword
 Cytoplasm; Initiation factor; Phosphoprotein; Protein biosynthesis; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 320 AA 
Protein Sequence
MPTGDFDSKP SWADQVEEEG EDDKCVTSEL LKGIPLPTGD TSPEPELLPG DPLPPPKEVI 60
NGNIKTVTEY KIEEDGKKFK IVRTFRIETR KASKAVARRK NWKKFGNSEF DPPGPNVATA 120
TVSDDVSMTF ITSKEDLNCQ EEEDPMNKLK GQKIVSCRIC KGDHWTTRCP YKDTLGPMQK 180
ELAEQLGLST GEKEKLPGEL EPVQAAQSKT GKYVPPSLRD GASRRGESMQ PNRRADDNAT 240
IRVTNLSEDT RETDLQELFR PFGSISRIYL AKDKTTGQSK GFAFISFHRR EDAARAIAGV 300
SGFGYDHLIL NVEWAKPSTN 320 
Gene Ontology
 GO:0016282; C:eukaryotic 43S preinitiation complex; IEA:HAMAP.
 GO:0033290; C:eukaryotic 48S preinitiation complex; IEA:HAMAP.
 GO:0005852; C:eukaryotic translation initiation factor 3 complex; IEA:HAMAP.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003743; F:translation initiation factor activity; IEA:HAMAP.
 GO:0001731; P:formation of translation preinitiation complex; IEA:HAMAP.
 GO:0006446; P:regulation of translational initiation; IEA:HAMAP. 
Interpro
 IPR017334; eIF3_g.
 IPR024675; eIF3g_N.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF12353; eIF3g
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS