CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032557
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Clathrin heavy chain, putative 
Protein Synonyms/Alias
  
Gene Name
 TGGT1_032170, TGVEG_084360 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Toxoplasma gondii 
NCBI Taxa ID
 5811 
Lysine Modification
Position
Peptide
Type
References
1488GHLAVVEKYLRETQHacetylation[1, 2]
Reference
 [1] Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii.
 Jeffers V, Sullivan WJ Jr.
 Eukaryot Cell. 2012 Jun;11(6):735-42. [PMID: 22544907]
 [2] Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii.
 Xue B, Jeffers V, Sullivan WJ, Uversky VN.
 Mol Biosyst. 2013 Apr 5;9(4):645-57. [PMID: 23403842] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1731 AA 
Protein Sequence
MAQQFPIQLH SVVNLADQGV SASSFRFGNV AMHGDKNLVV KDTETNELFI FSLSVREVHE 60
GRVSPSSPGF SFTKKPTQAE AALMHPSEKV VALRAKTEGS AGHMIQVLNL ETKVRLGTAQ 120
MNEPVVYWRW VAPTLLALVT DRAVYHWTVG ENGETTAEPE KVCSREGRLA DAVQIISYAV 180
DKDLKWCILT GISTQDGGKT IDGSMQLYSM ELKKQQQLEG HAACFNNIVI DEAVGPQPVI 240
CFTEKKRGSP DFKLHIRDIY SSRDGGQTPL RLAVDLRMPE DAPTDFPLSI HISQKFGVVY 300
IVTKGGYLIL LDALTGTELF RHRILQDAVF LATDSPQTGG ILTVNKRGLV CLCNINLQAL 360
IPYINQALVY VPNRQQIATS LAKRYGLPGA EETLMQEFNQ HFASGNFKTA ARIAATLKSG 420
VLRTAQVIQQ FKSVPTQPGQ TSAILVYFST LLEYDSLNAV ESLELVRPVA VQGRKDFVEK 480
WLREGKLECT EELGDVVRTL DAQLAVRVYR EAKAGAKVLQ TLTELGNFDE IIAFAKETKL 540
EADYAGLLRN LVNVHPENAV KFAQQLLSSE PPLADVTQVS EVLLQQHKYQ EFTSLMLDFL 600
KGNKPEQGPL QTRLLEVNLL HSPQVAETIF QMEMLTHFDR AKIAALCEKV GLSQRALELY 660
TDIADIKRVM LQSGGKISQE FTQQFFGNLP PDASLEILTD MLRSSSQNLQ AVVAVAIKFH 720
GQIGTTKLVE MFEKFSSYEG VFYFLGSILA FSSDPEVHFK YIEAAAKLNH TQEVERVCRE 780
SKCYEPQRVK EFLKQVKLPD PRPLIYVCDL HGYVTELAEY LFKNSLLKYI EVYVSRVNSA 840
NAPLVIGTLI DQDAAEDFIR NLLQSVRGGC SAQQLVEEFE KRNRLRLLLQ WLEARVAEGN 900
QEPAVHNALA KIYIDTNRDA ESFLKTNAYY DSLVVGKYCE ERDPHLAFTA YKRAWGACDE 960
QLVELTNKNG LFRLQARYLV ERQAPELWAY VLREENPHRR QAIDQVVSSA LPESSSADEV 1020
SAAVNAFINA QLPHELIELL EKIVLHNSDF SNNKNLQNLL ILTAMKADSS RIIDYVNRLH 1080
NYDGAAIAQV AMEYGLREEA FTIYKRFGLF GEAADTLLKS AEEGSEADLE RAVEFAQRCN 1140
EADVWRKLGR AQLRQKRVRD AIESFLKAGD GDVYKEVVEA AAAEDAYDAL VDFLLMARKK 1200
ITVKDQVIDS ELVYAYAKTD RLEEMDAFLS GTNTANVQAV GDRLFAEQRY KAAKLLYASL 1260
PNYAKLASCF VRLEDFAASV DAARKAKNPK TWKEVAFAAL SKGELKCAHA AALSLIVHPD 1320
HLDSLIERYE QLCLFKELIE LLEQGLQGER THVGLYTELG VLYATYESSK LMDYIRQHSG 1380
KVNIPRLIRA CERQSLWKEA VYLHMNYDEY EQAANCLIMH PAAWSHELFV QILQKVSNSD 1440
VFYRAISFYL EYHPLQLCLL LKSLDKKLDH SRVVQHVRKA GHLAVVEKYL RETQHLNITA 1500
VNEAVNELLV EGEDVDGLRE SILEYDNFDQ LALAQTLENH PRVEMRRLAA LLFKKNRKFK 1560
QAIELSKRDR QYQDAIDAAR DSGNTQLVGD LLRFFLADLE DPAGFAACLY TCYPLVKPDV 1620
ALELAWRHKC MDYCMPFLIQ VVREVTTRVD ALDKKEETRE KEEEKQKSAP NDYVPDYTMP 1680
PTGSPLLPGM GGLALMPPSY TPQSNAFPPT LGASGMMGSA PANLGQSFAP F 1731 
Gene Ontology
 GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
 GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR000547; Clathrin_H-chain/VPS_repeat.
 IPR016025; Clathrin_H-chain_link/propller.
 IPR001473; Clathrin_H-chain_propeller_N.
 IPR016341; Clathrin_heavy_chain.
 IPR011990; TPR-like_helical. 
Pfam
 PF00637; Clathrin 
SMART
 SM00299; CLH 
PROSITE
  
PRINTS