CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040180
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein very KIND 
Protein Synonyms/Alias
  
Gene Name
 Kndc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
182VQFLSLVKKYLQVMYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 744 AA 
Protein Sequence
XPTALSDIDS DTLSQGNFEV GFRSQKSIKV TREQQPEAEV GGQPGPSQDS TSHASDTVAR 60
LARSEDGGPA GSPGASDFQN CSPGWSSAFY EADCFGADVY NYVKDLERQK TNGHTELEAQ 120
SPELEQQLMI EKRNYRKTLK FYQKLLQKEK RNKGSEVRTM LSKLRGQLDE MKSKVQFLSL 180
VKKYLQVMYA ERWGLEPCAL PVIVNIAAAP CDTLDFSPLD ESSSLIFYNV NKHPGSGRQK 240
KARILQAGTP LGLMAYLYSS DAFLEGYVQQ FLYTFRYFCT PHDFLHFLLD RISSTLSRAH 300
QDPTSTFTKI YRRSLCVLQA WVEDCYTVDF IRNAGLLGQL EDFISSKILP LDGTAEHLLA 360
LLEVGTERRA DSASRGADLE DPKEAEEDTR PFNALCKRFS EDGITRKSFS WRLPRGNGLV 420
LPHHKERQYT IASALPKPCF FEDFYGPYAK ASEKGPYFLT EYSTNQLFTQ LTLLQQELFQ 480
KCHPVHFLNS RALGVMDKSA AIPKASSSES LSAKTCSLFL PNYVQDKYLL QLLRNADDVS 540
TWVAAEIVTS HTSKLQVNLL SKFLLIAKSC YEQRNFATAM QILGGLEHLA VRQSPAWRIL 600
PAKIAEVMEE LKAVEVFLKS DSLCLMEGRR FRAQPTLPSA HLLAMHIQQL ETGGFTMTNG 660
AHRWSKLRNI AKVASQVHAF QENPYTFSPD PKLQAHLKQR IARFSGADVS ILAADNRANF 720
HQIPGEKHSR KIQDKLRRMK ATFQ 744 
Gene Ontology
 GO:0030425; C:dendrite; IDA:MGI.
 GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:MGI.
 GO:0043025; C:neuronal cell body; IDA:MGI.
 GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
 GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:MGI.
 GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.
 GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.
 GO:0048814; P:regulation of dendrite morphogenesis; IDA:MGI.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR000651; Ras-like_Gua-exchang_fac_N.
 IPR023578; Ras_GEF_dom.
 IPR001895; RasGRF_CDC25. 
Pfam
 PF00617; RasGEF
 PF00618; RasGEF_N 
SMART
  
PROSITE
 PS50009; RASGEF_CAT
 PS50212; RASGEF_NTER 
PRINTS