CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038325
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transporter 
Protein Synonyms/Alias
  
Gene Name
 Slc6a8 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
18YSVSGDEKKGPLIVSubiquitination[1]
33GPDGAPAKGDGPAGLubiquitination[1]
217VIEFWENKVLRLSTGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 630 AA 
Protein Sequence
MAKKSAENGI YSVSGDEKKG PLIVSGPDGA PAKGDGPAGL GAPGGRLAVP PRETWTRQMD 60
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 120
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 180
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSTGLEVPGA LNWEVTLCLL 240
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL 300
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYNG TSFFAGFVVF SILGFMATEQ 360
GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV GVEGFITGLL 420
DLLPASYYFR FQREISVALC CALCFVIDLS MVTDVSGGKG GMYVFQLFDY YSASGTTLLW 480
QAFWECVVVA WVYGADRFMD DIACMIGYRP CPWMKWCWSF FTPLVCMGIF IFNIVYYEPL 540
VYNNTYVYPW WGEAMGWAFA LSSMLCVPLH LLGCLLRAKG TMAERWQHLT QPIWGLHHLE 600
YRAQDADVRG LTTLTPVSES SKVVVVESVM 630 
Gene Ontology
 GO:0005887; C:integral to plasma membrane; IEA:InterPro.
 GO:0005309; F:creatine:sodium symporter activity; IEA:InterPro.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro. 
Interpro
 IPR000175; Na/ntran_symport.
 IPR002984; Na/ntran_symport_creatine. 
Pfam
 PF00209; SNF 
SMART
  
PROSITE
 PS00610; NA_NEUROTRAN_SYMP_1
 PS00754; NA_NEUROTRAN_SYMP_2
 PS50267; NA_NEUROTRAN_SYMP_3 
PRINTS
 PR01199; CRTTRANSPORT.
 PR00176; NANEUSMPORT.