UniProt Accession

 SP17_HUMAN; Q15506; B2R4F2; Q9BXF7 

Genbank Protein ID

 Z48570; AF334735; AF334810; AK311806; CH471065; BC032457 

Genbank Nucleotide ID

 CAA88459.1; AAK20878.1; AAK28125.1; BAG34749.1; EAW67592.1; AAH32457.1 

Protein Name

 Sperm surface protein Sp17 

Protein Synonyms/Alias

 Cancer/testis antigen 22; CT22; Sp17-1; Sperm autoantigenic protein 17; Sperm protein 17 

Gene Name

 SPA17 

Gene Synonyms/Alias

 SP17 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
52	SLLEKREKTNFDPAE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity). 

Sequence Annotation

 DOMAIN 114 143 IQ.  

Keyword

 Complete proteome; Membrane; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 151 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:BHF-UCL.
 GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
 GO:0031514; C:motile cilium; IDA:BHF-UCL.
 GO:0072372; C:primary cilium; IDA:BHF-UCL.
 GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.
 GO:0007339; P:binding of sperm to zona pellucida; IEA:InterPro.
 GO:0001539; P:ciliary or flagellar motility; IDA:BHF-UCL.
 GO:0007165; P:signal transduction; IEA:InterPro.
 GO:0007338; P:single fertilization; TAS:ProtInc.
 GO:0007283; P:spermatogenesis; TAS:ProtInc. 

Interpro

 IPR003117; cAMP_dep_PK_reg_su_I/II_a/b.
 IPR000048; IQ_motif_EF-hand-BS.
 IPR012105; Sp17. 

Pfam

 PF00612; IQ
 PF02197; RIIa 

SMART

 SM00015; IQ
 SM00394; RIIa 

PROSITE

 PS50096; IQ 

PRINTS