CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024478
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Putative nuclear envelope pore membrane protein POM 121B 
Protein Synonyms/Alias
  
Gene Name
 POM121B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
125EDLDLEKKASLQWFNubiquitination[1]
321PIFTAPPKSEKEGPTacetylation[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861] 
Functional Description
 Putative component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; mRNA transport; Nuclear pore complex; Nucleus; Protein transport; Reference proteome; Repeat; Translocation; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 834 AA 
Protein Sequence
MSRRVRTSEL WKRNGPSSSP FSSPASSRSQ TPERPAKKIR EEEMCHHSSS STPLAADKES 60
QGEKAADTTP RKKQNSNSQS TPGSSGQRKR KVQLLPSRRG EQLTLPPPPQ LGYSITAEDL 120
DLEKKASLQW FNQALEDKSD AASNSVTETP PITQPSFTFT LPAAAPASPP TSLLAPSTNP 180
LLESLKKMQT PPSLPPCPES AGAATTEALS PPKTPNLLPP LGLSQSGPPG LLPSPSFDSN 240
PPTTLLGLIP APSMVPATDT KAPPTLQAET TTKPQATSAP SPAPKQSFLF GTQNTSPSSP 300
AAPAASSASP MFKPIFTAPP KSEKEGPTPP GPSVSATAPS SSSLPTTTST TAPTFQPVFS 360
SMGPPASVPL PAPFFKQTTT PATAPTTTAP LFTGLASATS AVAPITSASP STDSASKPAF 420
GFGINSVSSS SVSTTTSTAT AASQPFLFGA PQASAASFTP AMGSIFQFGK PPALPTTTTV 480
TTFSQSLPTA VPTATSSSAA DFSGFGSTLA TSAPATSSQP TLTFSNTSTP TFNIPFGSSA 540
KSPLPSYPGA NPQPAFGAAE GQPPGAAKPA LTPSFGSSFT FGNSAAPAAA PTPAPPSMIK 600
IVPAHVPTPI QPTFGGATHS AFGLKATASA FGAPASSQPA FGGSTAVFSF GAATSSGFGA 660
TTQTASSGSS SSVFGSTTPS PFTFGGSAAP AGSGSFGINV ATPGSSATTG AFSFGAGQSG 720
STATSTPFAG GLGQNALGTT GQSTPFAFNV GSTTESKPVF GGTATPTFGL NTPAPGVGTS 780
GSSLSFGASS APAQGFVGVA PFGSAAPSFS IGAGSKTLGA RQRLQARRQH TRKK 834 
Gene Ontology
 GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
 GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW. 
Interpro
 IPR026054; Nucleoporin.
 IPR026090; POM121. 
Pfam
  
SMART
  
PROSITE
  
PRINTS