UniProt Accession

 NAT5_YEAST; Q08689; D6W2V4 

Genbank Protein ID

 Z75161; AY557750; BK006948 

Genbank Nucleotide ID

 CAA99475.1; AAS56076.1; DAA11020.1 

Protein Name

 N-terminal acetyltransferase A complex subunit NAT5 

Protein Synonyms/Alias

 NatA complex subunit NAT5 

Gene Name

 NAT5 

Gene Synonyms/Alias

 YOR253W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
110	RHKSIGSKLLKFAED	ubiquitination	[1]
172	EQDAILLKKHIS***	acetylation	[2]
172	EQDAILLKKHIS***	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Non-essential component of the NatA N-terminal acetyltransferase, which catalyzes acetylation of proteins beginning with Met-Ser, Met-Gly and Met-Ala. N-acetylation plays a role in normal eukaryotic translation and processing, protect against proteolytic degradation and protein turnover. 

Sequence Annotation

 DOMAIN 14 176 N-acetyltransferase.  

Keyword

 Acyltransferase; Complete proteome; Cytoplasm; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 176 AA 

Protein Sequence

Gene Ontology

 GO:0031415; C:NatA complex; IDA:SGD.
 GO:0004596; F:peptide alpha-N-acetyltransferase activity; ISA:SGD.
 GO:0006474; P:N-terminal protein amino acid acetylation; ISA:SGD. 

Interpro

 IPR016181; Acyl_CoA_acyltransferase.
 IPR000182; GNAT_dom. 

Pfam

 PF00583; Acetyltransf_1 

SMART

  

PROSITE

 PS51186; GNAT 

PRINTS