CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038777
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Hepatocyte nuclear factor 4-gamma 
Protein Synonyms/Alias
  
Gene Name
 Hnf4g 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
240HLLLGATKRSMMYKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 462 AA 
Protein Sequence
MCVSQSMMRV SEPILDMDMG NYSEVLDPTY STLEFDTMQI LYNPNDSSAP ETTSMNTTDS 60
GVNCLCAICG DRATGKHYGA SSCDGCKGFF RRSIRKSHVY SCRFSRQCVV DKDKRNQCRY 120
CRLRKCFRAG MKKEAVQNER DRISTRRSTY EGSNIPSINT LAQAEVRSCQ ISVPSPSSST 180
DINIKKIASI SDVCESMKQQ LLVLVEWAKY IPAFCELPLD DQVALLRAHA GEHLLLGATK 240
RSMMYKDILL LGNHYVIHRN SCEVEVSRVA NRVLDELVRP FQEIQIDDNE YACLKAIVFF 300
DPDAKGLSDP VKIKNMRFQV QISLEDYIND RQYDSRGRFG ELLLLLPTLQ SITWQMIEQI 360
QFVKLFGMVK IDNLLQEMLL GGAANDGSHL HHPMHPHLSQ DPLTGQTILL GPMSTLVHTD 420
QIATPETPLP SPPQGSGQEP YKITANQASV ISHQSLSKQK QL 462 
Gene Ontology
 GO:0005667; C:transcription factor complex; ISS:MGI.
 GO:0004879; F:ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; IEA:InterPro.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0030522; P:intracellular receptor signaling pathway; IEA:GOC.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI. 
Interpro
 IPR003068; COUP_TF.
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR000536; Nucl_hrmn_rcpt_lig-bd_core.
 IPR001723; Str_hrmn_rcpt.
 IPR001628; Znf_hrmn_rcpt.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00104; Hormone_recep
 PF00105; zf-C4 
SMART
 SM00430; HOLI
 SM00399; ZnF_C4 
PROSITE
 PS00031; NUCLEAR_REC_DBD_1
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR01282; COUPTNFACTOR.
 PR00398; STRDHORMONER.
 PR00047; STROIDFINGER.