UniProt Accession

 O88321_RAT; O88321 

Genbank Protein ID

 AABR06019271; AB017188; CH474015 

Genbank Nucleotide ID

 BAA32596.1; EDL85758.1 

Protein Name

 Antisecretory factor 

Protein Synonyms/Alias

 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 4, isoform CRA_a; Protein Psmd4 

Gene Name

 Psmd4 

Gene Synonyms/Alias

 rCG_51785 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
74	DTGRILSKLHTVQPK	acetylation	[1]
74	DTGRILSKLHTVQPK	ubiquitination	[2]
122	SPVEDNEKDLVKLAK	acetylation	[1]
126	DNEKDLVKLAKRLKK	acetylation	[1]
368	SLASQATKDGKKDKK	acetylation	[1]
371	SQATKDGKKDKKEEE	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Proteasome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 380 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0008540; C:proteasome regulatory particle, base subcomplex; IEA:InterPro.
 GO:0042044; P:fluid transport; NAS:RGD.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 

Interpro

 IPR027040; Proteasome_su_Rpn10.
 IPR003903; Ubiquitin-int_motif.
 IPR002035; VWF_A. 

Pfam

 PF02809; UIM 

SMART

 SM00726; UIM
 SM00327; VWA 

PROSITE

 PS50330; UIM
 PS50234; VWFA 

PRINTS