CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003439
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 AMP nucleosidase 
Protein Synonyms/Alias
  
Gene Name
 amn 
Gene Synonyms/Alias
 b1982; JW1963 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
356RALYDATKLVSGRPGacetylation[1]
429TLLCVSDKPLHGEIKacetylation[2]
436KPLHGEIKLPGQANRacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 
Functional Description
 Involved in regulation of AMP concentrations. 
Sequence Annotation
  
Keyword
 3D-structure; Allosteric enzyme; Complete proteome; Direct protein sequencing; Hydrolase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 484 AA 
Protein Sequence
MNNKGSGLTP AQALDKLDAL YEQSVVALRN AIGNYITSGE LPDENARKQG LFVYPSLTVT 60
WDGSTTNPPK TRAFGRFTHA GSYTTTITRP TLFRSYLNEQ LTLLYQDYGA HISVQPSQHE 120
IPYPYVIDGS ELTLDRSMSA GLTRYFPTTE LAQIGDETAD GIYHPTEFSP LSHFDARRVD 180
FSLARLRHYT GTPVEHFQPF VLFTNYTRYV DEFVRWGCSQ ILDPDSPYIA LSCAGGNWIT 240
AETEAPEEAI SDLAWKKHQM PAWHLITADG QGITLVNIGV GPSNAKTICD HLAVLRPDVW 300
LMIGHCGGLR ESQAIGDYVL AHAYLRDDHV LDAVLPPDIP IPSIAEVQRA LYDATKLVSG 360
RPGEEVKQRL RTGTVVTTDD RNWELRYSAS ALRFNLSRAV AIDMESATIA AQGYRFRVPY 420
GTLLCVSDKP LHGEIKLPGQ ANRFYEGAIS EHLQIGIRAI DLLRAEGDRL HSRKLRTFNE 480
PPFR 484 
Gene Ontology
 GO:0008714; F:AMP nucleosidase activity; IDA:EcoCyc.
 GO:0044209; P:AMP salvage; IEA:UniProtKB-UniPathway. 
Interpro
 IPR011271; AMP_nucleosidase.
 IPR018953; AMP_nucleoside_Pase_N.
 IPR018017; Nucleoside_phosphorylase.
 IPR000845; Nucleoside_phosphorylase_d. 
Pfam
 PF10423; AMNp_N
 PF01048; PNP_UDP_1 
SMART
  
PROSITE
  
PRINTS