CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011299
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LIM domain and RING finger protein YDR266C 
Protein Synonyms/Alias
  
Gene Name
 YDR266C 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
264PASPQYFKDYNQLFDubiquitination[1]
294DNKFVVFKDELELQAubiquitination[1]
383KYYLENSKEDFNKFSubiquitination[1]
438TFPKNSSKYNNLNAIubiquitination[1]
502IKNLPTLKSPSASYDubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
  
Sequence Annotation
 DOMAIN 222 292 LIM zinc-binding.
 ZN_FING 64 104 RING-type.
 MOD_RES 57 57 Phosphothreonine.
 MOD_RES 354 354 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; LIM domain; Metal-binding; Phosphoprotein; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MSESVKENVT PTRNFRRTQG PQNNTKPHND RKNFRRKQKK NNLSAEPNLT TSSADDTDEE 60
NELCVICARK LTYVSLTPCH HKTCHICGFR QRALYNKKSC LICRTENEEV MFTDRIDGDI 120
SDKYNFCEKN EKYGINFTSE EVATETLNLL KFFCPLSKDE QVCDFGSFKK YNEHLKSEHN 180
RMICLICATH KHAFPCELEI FTQNQLRNHQ TKGNSEGFKG HPMCAFCSGK RFYSDDELYI 240
HMRNQHEKCH ICDKMNPASP QYFKDYNQLF DHFKHSHYVC TVQTCLDNKF VVFKDELELQ 300
AHILQEHGNI LKGKPKFFQS ELSTFISAPS RVIRERDDYD LPSISSLPGS SSGSRTDVRS 360
ASSPEESRLR LAERAKYYLE NSKEDFNKFS SYNEDYSKGR LSAEKLLESY KLLFTKPNAD 420
VYLLIHNLAE TFPKNSSKYN NLNAIYEQRE QTLARQTSLP SLSSDSSLSM SIGRGHWGGT 480
NDGGSAGAAL GVRNIKNLPT LKSPSASYDP FATTVKKNTL RPVQNIKRTT PQSVSYRTST 540
NTVAFSPTYL ESKKGSSSTS LNNSKDKLKS LNLPQLPPPK PKVQIPGLNR PQIADPKQWG 600
KKSSTQDTNV HDNLRELNTT SGGNKKKGKQ KQLLFHIGV 639 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0036205; P:histone catabolic process; IMP:SGD.
 GO:0016574; P:histone ubiquitination; IDA:SGD. 
Interpro
 IPR015880; Znf_C2H2-like.
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00184; RING
 SM00355; ZnF_C2H2 
PROSITE
 PS00478; LIM_DOMAIN_1
 PS50023; LIM_DOMAIN_2
 PS00518; ZF_RING_1
 PS50089; ZF_RING_2
 PS00028; ZINC_FINGER_C2H2_1 
PRINTS