CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038629
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Retinoic acid receptor RXR-gamma 
Protein Synonyms/Alias
  
Gene Name
 Rxrg 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
259VLFNPDAKGLSNPSEubiquitination[1]
295EQPGRFAKLLLRLPAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 340 AA 
Protein Sequence
MNYPSTSPGS LVKHICAICG DRSSGKHYGV YSCEGCKGFF KRTIRKDLIY TCRDNKDCLI 60
DKRQRNRCQY CRYQKCLVMG MKREAVQEER QRSRERAESE AECASSSHED MPVERILEAE 120
LAVEPKTESY GDMNVENSTN DPVTNICHAA DKQLFTLVEW AKRIPHFSDL TLEDQVILLR 180
AGWNELLIAS FSHRSVSVQD GILLATGLHV HRSSAHSAGV GSIFDRVLTE LVSKMKDMQM 240
DKSELGCLRA IVLFNPDAKG LSNPSEVETL REKVYATLEA YTKQKYPEQP GRFAKLLLRL 300
PALRSIGLKC LEHLFFFKLI GDTPIDSFLM EMLETPLQIT 340 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0004886; F:9-cis retinoic acid receptor activity; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IGI:MGI.
 GO:0003707; F:steroid hormone receptor activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0007507; P:heart development; IEA:Compara.
 GO:0030182; P:neuron differentiation; IEA:Compara.
 GO:0007422; P:peripheral nervous system development; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.
 GO:0031641; P:regulation of myelination; IEA:Compara.
 GO:0032526; P:response to retinoic acid; IEA:Compara.
 GO:0007519; P:skeletal muscle tissue development; IEA:Compara. 
Interpro
 IPR008946; Nucl_hormone_rcpt_ligand-bd.
 IPR000536; Nucl_hrmn_rcpt_lig-bd_core.
 IPR000003; Retinoid-X_rcpt/HNF4.
 IPR001723; Str_hrmn_rcpt.
 IPR001628; Znf_hrmn_rcpt.
 IPR013088; Znf_NHR/GATA. 
Pfam
 PF00104; Hormone_recep
 PF00105; zf-C4 
SMART
 SM00430; HOLI
 SM00399; ZnF_C4 
PROSITE
 PS00031; NUCLEAR_REC_DBD_1
 PS51030; NUCLEAR_REC_DBD_2 
PRINTS
 PR00545; RETINOIDXR.
 PR00398; STRDHORMONER.
 PR00047; STROIDFINGER.