| Tag | Content |
|---|
| CPLM ID | CPLM-005193 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alpha-internexin |
Protein Synonyms/Alias | Alpha-Inx |
Gene Name | Ina |
Gene Synonyms/Alias | Inexa |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 95 | KIIRTNEKEQLQGLN | ubiquitination | [1] | | 278 | QYESLAAKNLQSAEE | ubiquitination | [1] |
|
Reference | [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis. Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J. J Proteome Res. 2012 Sep 7;11(9):4722-32. [ PMID: 22871113] |
Functional Description | Class-IV neuronal intermediate filament that is able to self-assemble. It is involved in the morphogenesis of neurons. It may form an independent structural network without the involvement of other neurofilaments or it may cooperate with NF-L to form the filamentous backbone to which NF-M and NF-H attach to form the cross-bridges (By similarity). |
Sequence Annotation | REGION 1 87 Head.
REGION 88 408 Rod.
REGION 88 129 Coil 1A.
REGION 130 142 Linker 1.
REGION 143 238 Coil 1B.
REGION 239 262 Linker 2.
REGION 263 408 Coil 2.
REGION 409 505 Tail.
MOD_RES 72 72 Phosphoserine (By similarity).
MOD_RES 290 290 N6-acetyllysine (By similarity).
MOD_RES 335 335 Phosphoserine (By similarity).
MOD_RES 502 502 Phosphoserine (By similarity). |
Keyword | Acetylation; Coiled coil; Complete proteome; Developmental protein; Differentiation; Direct protein sequencing; Glycoprotein; Intermediate filament; Neurogenesis; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 505 AA |
Protein Sequence | MSFGSEHYLC SASSYRKVFG DGSRLSARLS GPGASGSFRS QSLSRSNVAS TAACSSASSL 60
GLGLAYRRLP ASDGLDLSQA AARTNEYKII RTNEKEQLQG LNDRFAVFIE KVHQLETQNR 120
ALEAELAALR QRHAEPSRVG ELFQRELREL RAQLEEASSA RAQALLERDG LAEEVQRLRA 180
RCEEESRGRE GAERALKAQQ RDVDGATLAR LDLEKKVESL LDELAFVRQV HDEEVAELLA 240
TLQASSQAAA EVDVAVAKPD LTSALREIRA QYESLAAKNL QSAEEWYKSK FANLNEQAAR 300
STEAIRASRE EIHEYRRQLQ ARTIEIEGLR GANESLERQI LELEERHSAE VAGYQDSIGQ 360
LESDLRNTKS EMARHLREYQ DLLNVKMALD IEIAAYRKLL EGEETRFSTS GLSISGLNPL 420
PNPSYLLPPR ILSSTTSKVS SAGLSLKKEE EEEEEEEEGA SKEVTKKTSK VGESFEETLE 480
ETVVSTKKTE KSTIEEITTS SSQKM 505 |
Gene Ontology | GO:0005882; C:intermediate filament; IEA:UniProtKB-KW. GO:0005198; F:structural molecule activity; IEA:InterPro. GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. GO:0007399; P:nervous system development; IEA:UniProtKB-KW. GO:0042246; P:tissue regeneration; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |