CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015022
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Major facilitator superfamily domain-containing protein 5 
Protein Synonyms/Alias
  
Gene Name
 MFSD5 
Gene Synonyms/Alias
 UNQ832/PRO1759 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
367SMSFLRRKVIPETEQubiquitination[1, 2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
MLVTAYLAFV GLLASCLGLE LSRCRAKPPG RACSNPSFLR FQLDFYQVYF LALAADWLQA 60
PYLYKLYQHY YFLEGQIAIL YVCGLASTVL FGLVASSLVD WLGRKNSCVL FSLTYSLCCL 120
TKLSQDYFVL LVGRALGGLS TALLFSAFEA WYIHEHVERH DFPAEWIPAT FARAAFWNHV 180
LAVVAGVAAE AVASWIGLGP VAPFVAAIPL LALAGALALR NWGENYDRQR AFSRTCAGGL 240
RCLLSDRRVL LLGTIQALFE SVIFIFVFLW TPVLDPHGAP LGIIFSSFMA ASLLGSSLYR 300
IATSKRYHLQ PMHLLSLAVL IVVFSLFMLT FSTSPGQESP VESFIAFLLI ELACGLYFPS 360
MSFLRRKVIP ETEQAGVLNW FRVPLHSLAC LGLLVLHDSD RKTGTRNMFS ICSAVMVMAL 420
LAVVGLFTVV RHDAELRVPS PTEEPYAPEL 450 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR008509; DUF791.
 IPR016196; MFS_dom_general_subst_transpt. 
Pfam
 PF05631; DUF791 
SMART
  
PROSITE
 PS50850; MFS 
PRINTS