CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027104
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Myo1b protein 
Protein Synonyms/Alias
 Unconventional myosin-Ib 
Gene Name
 Myo1b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
68LPIYSPEKVEDYRNRubiquitination[1]
156LEAFGNAKTVRNDNSubiquitination[1]
192ISNYLLEKSRVVKQPubiquitination[1]
241YLSLDSAKVNGVDDAubiquitination[1]
301GLDESKIKDKNELKEacetylation[2]
529QVEGFVDKNNDLLYRubiquitination[1]
565NPAKVNLKRPPTAGSubiquitination[1]
588LMRNLQTKNPNYIRCubiquitination[1]
935DQFTDQQKLIYEEKLubiquitination[1]
972GAYLEINKNPKYKKLubiquitination[1]
986LKDAIEEKIIIAEVVubiquitination[1]
1052GFFAVHLKEGSEAASubiquitination[1]
1086RTTLSQTKQKLNIEIubiquitination[1]
1109RQDKVCVKFIQGNQKubiquitination[1]
1116KFIQGNQKNGSVPTCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Motor protein; Myosin; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1136 AA 
Protein Sequence
MAKMEVKSSL LDNMIGVGDM VLLEPLNEET FIDNLKKRFD HNEIYTYIGS VVISVNPYRS 60
LPIYSPEKVE DYRNRNFYEL SPHIFALSDE AYRSLRDQDK DQCILITGES GAGKTEASKL 120
VMSYVAAVCG KGAEVNQVKE QLLQSNPVLE AFGNAKTVRN DNSSRFGKYM DIEFDFKGDP 180
LGGVISNYLL EKSRVVKQPR GERNFHVFYQ LLSGASEELL YKLKLERDFS RYNYLSLDSA 240
KVNGVDDAAN FRTVRNAMQI VGFLDHEAEA VLEVVAAVLK LGNIEFKPES RVNGLDESKI 300
KDKNELKEIC ELTSIDQVVL ERAFSFRTVE AKQEKVSTTL NVAQAYYARD ALAKNLYSRL 360
FSWLVNRINE SIKAQTKVRK KVMGVLDIYG FEIFEDNSFE QFIINYCNEK LQQIFIELTL 420
KEEQEEYIRE DIEWTHIDYF NNAIICDLIE NNTNGILAML DEECLRPGTV TDETFLEKLN 480
QVCATHQHFE SRMSKCSRFL NDTTLPHSCF RIQHYAGKVL YQVEGFVDKN NDLLYRDLSQ 540
AMWKAGHSLI KSLFPEGNPA KVNLKRPPTA GSQFKASVAT LMRNLQTKNP NYIRCIKPND 600
KKAAHIFNES LVCHQIRYLG LLENVRVRRA GYAFRQAYEP CLERYKMLCK QTWPHWKGPA 660
RSGVEVLFNE LEIPVEEHSF GRSKIFIRNP RTLFQLEDLR KQRLEDLATL IQKIYRGWKC 720
RTHFLLMKRS QVVIAAWYRR YAQQKRYQQI KSSALVIQSY IRGWKARKIL RELKHQKRCK 780
EAATTIAAYW HGTQARRELR RLKDEARNKH AIAVIWAYWL GSKARRELKR LKEEARRKHA 840
VAVIWAYWLG LKVRREYRKF FRANAGKKIY EFTLQRIVQK YLLEMKNKMP SLSPIDKNWP 900
SRPYLFLDST HKELKRIFHL WRCKKYRDQF TDQQKLIYEE KLEASELFKD KKALYPSSVG 960
QPFQGAYLEI NKNPKYKKLK DAIEEKIIIA EVVNKINRAN GKSTSRIFLL TNNNLLLADQ 1020
KSGQIKSEVP LVDVTKVSMS SQNDGFFAVH LKEGSEAASK GDFLFSSDHL IEMATKLYRT 1080
TLSQTKQKLN IEISDEFLVQ FRQDKVCVKF IQGNQKNGSV PTCKRKNNRL LEVAVP 1136 
Gene Ontology
 GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003774; F:motor activity; IEA:InterPro. 
Interpro
 IPR000048; IQ_motif_EF-hand-BS.
 IPR001609; Myosin_head_motor_dom.
 IPR010926; Myosin_tail_2.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00612; IQ
 PF00063; Myosin_head
 PF06017; Myosin_TH1 
SMART
 SM00015; IQ
 SM00242; MYSc 
PROSITE
 PS50096; IQ 
PRINTS
 PR00193; MYOSINHEAVY.