UniProt Accession

 F8VZC8_HUMAN; F8VZC8 

Genbank Protein ID

 AC018922; AC128657 

Genbank Nucleotide ID

  

Protein Name

 Transporter 

Protein Synonyms/Alias

  

Gene Name

 SLC6A15 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
136	NLASVTYKRGRVLKE	ubiquitination	[1, 2]
142	YKRGRVLKEPVNLEG	ubiquitination	[3]
158	DTSLIHGKIPSEMPS	ubiquitination	[2]
170	MPSPNFGKNIYRKQS	ubiquitination	[2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin.
 Oshikawa K, Matsumoto M, Oyamada K, Nakayama KI.
 J Proteome Res. 2012 Feb 3;11(2):796-807. [PMID: 22053931] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Reference proteome; Symport; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 208 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005328; F:neurotransmitter:sodium symporter activity; IEA:InterPro.
 GO:0005298; F:proline:sodium symporter activity; IEA:Compara.
 GO:0015820; P:leucine transport; IEA:Compara. 

Interpro

 IPR000175; Na/ntran_symport. 

Pfam

 PF00209; SNF 

SMART

  

PROSITE

 PS50267; NA_NEUROTRAN_SYMP_3 

PRINTS

 PR00176; NANEUSMPORT.