UniProt Accession

 H0YCV2_HUMAN; H0YCV2 

Genbank Protein ID

 AC124068 

Genbank Nucleotide ID

  

Protein Name

 DNA polymerase subunit gamma-1 

Protein Synonyms/Alias

  

Gene Name

 POLG 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
7	*ARACLQKLKGTTEL	ubiquitination	[1]
9	RACLQKLKGTTELLP	ubiquitination	[1]
89	GRRDNLAKLPTGTTL	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 228 AA 

Protein Sequence

Gene Ontology

 GO:0005760; C:gamma DNA polymerase complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
 GO:0006260; P:DNA replication; IEA:InterPro. 

Interpro

 IPR002297; DNA-dir_DNA_pol_A_mt.
 IPR001098; DNA-dir_DNA_pol_A_palm_dom. 

Pfam

 PF00476; DNA_pol_A 

SMART

  

PROSITE

  

PRINTS