CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-044374
UniProt Accession
J3KPH2_HUMAN
;
J3KPH2
Genbank Protein ID
AC129492
;
CH471108
Genbank Nucleotide ID
EAW90093.1
Protein Name
Arachidonate lipoxygenase 3, isoform CRA_a
Protein Synonyms/Alias
Epidermis-type lipoxygenase 3
Gene Name
ALOXE3
Gene Synonyms/Alias
hCG_31289
Created Date
July 27, 2013
Organism
Homo sapiens (Human)
NCBI Taxa ID
9606
Lysine Modification
Position
Peptide
Type
References
331
DKKFALT
K
TTTCVDQ
ubiquitination
[1]
Reference
[1] Global identification of modular cullin-RING ligase substrates.
Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
Cell. 2011 Oct 14;147(2):459-74. [
PMID: 21963094
]
Functional Description
Sequence Annotation
Keyword
Complete proteome; Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
867 AA
Protein Sequence
MGRNRSWGTL GSGRTSTPGH QSGPLTRRRA VSQLYRRYLL FSISASDPSL RSGTQAPDIH 60
LGEPARGTGC VRGKQTSIRV QDCGRREEAR AASRELRREK AQEHPRESWA HPQPYPAPQP 120
LALRPETQPC PACRSSPPGR LLLRPALPGH PFLLPIMAVY RLCVTTGPYL RAGTLDNISV 180
TLVGTCGESP KQRLDRMGRD FAPGSVQKYK VRCTAELGEL LLLRVHKERY AFFRKDSWYC 240
SRICVTEPDG SVSHFPCYQW IEGYCTVELR PGTARTICQD SLPLLLDHRT RELRARQECY 300
RWKIYAPGFP CMVDVNSFQE MESDKKFALT KTTTCVDQGD SSGNRYLPGF PMKIDIPSLM 360
YMEPNVRYSA TKTISLLFNA IPASLGMKLR GLLDRKGSWK KLDDMQNIFW CHKTFTTKYV 420
TEHWCEDHFF GYQYLNGVNP VMLHCISSLP SKLPVTNDMV APLLGQDTCL QTELERGNIF 480
LADYWILAEA PTHCLNGRQQ YVAAPLCLLW LSPQGALVPL AIQLSQTPGP DSPIFLPTDS 540
EWDWLLAKTW VRNSEFLVHE NNTHFLCTHL LCEAFAMATL RQLPLCHPIY KLLLPHTRYT 600
LQVNTIARAT LLNPEGLVDQ VTSIGRQGLI YLMSTGLAHF TYTNFCLPDS LRARGVLAIP 660
NYHYRDDGLK IWAAIESFVS EIVGYYYPSD ASVQQDSELQ AWTGEIFAQA FLGRESSGFP 720
SRLCTPGEMV KFLTAIIFNC SAQHAAVNSG QHDFGAWMPN APSSMRQPPP QTKGTTTLKT 780
YLDTLPEVNI SCNNLLLFWL VSQEPKDQRP LGTYPDEHFT EEAPRRSIAA FQSRLAQISR 840
DIQERNQGLA LPYTYLDPPL IENSVSI 867
Gene Ontology
GO:0046872
; F:metal ion binding; IEA:UniProtKB-KW.
GO:0016702
; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.
Interpro
IPR008976
; Lipase_LipOase.
IPR000907
; LipOase.
IPR013819
; LipOase_C.
IPR020834
; LipOase_CS.
IPR020833
; LipOase_Fe_BS.
IPR001024
; LipOase_LH2.
Pfam
PF00305
; Lipoxygenase
PF01477
; PLAT
SMART
SM00308
; LH2
PROSITE
PS00711
; LIPOXYGENASE_1
PS00081
; LIPOXYGENASE_2
PS51393
; LIPOXYGENASE_3
PS50095
; PLAT
PRINTS
PR00087
; LIPOXYGENASE.