CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013903
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative mitochondrial import inner membrane translocase subunit Tim23B 
Protein Synonyms/Alias
  
Gene Name
 TIMM23B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
68ILPTGANKTRGRFELubiquitination[1, 2]
101NGLRLGLKETQNMAWubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May participate in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane. the PAM complex (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport; Reference proteome; Translocation; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 257 AA 
Protein Sequence
MEGGGGSGNK TTGGLAGFFG AGGAGYSHAD LAGVPLTGMN PLSPYLNVDP RYLVQDTDEF 60
ILPTGANKTR GRFELAFFTI GGCCMTGAAF GAMNGLRLGL KETQNMAWSK PRNVQILNMV 120
TRQGALWANT LGSLALLYSA FGVIIEKTRG AEDDLNTVAA GTMTGMLYKC TETGFHHGAQ 180
ANFQSEIIFR FLTRFFYAKK KASYSQISQK NLDFTILLRL KTLRSVESKC YVIFVVDELL 240
KNRIPQRIKC LMHNKPT 257 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005744; C:mitochondrial inner membrane presequence translocase complex; IEA:InterPro.
 GO:0015450; F:P-P-bond-hydrolysis-driven protein transmembrane transporter activity; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; IEA:InterPro. 
Interpro
 IPR003397; Tim17/Tim22/Tim23/PMP24.
 IPR005681; Tim23. 
Pfam
 PF02466; Tim17 
SMART
  
PROSITE
  
PRINTS