CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038678
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Homeobox protein cut-like 1 
Protein Synonyms/Alias
  
Gene Name
 Cux1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
399LEVLLLEKNRSLQSEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; DNA-binding; Homeobox; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1426 AA 
Protein Sequence
MAANVGSMFQ YWKRFDLQQL QRELDATATV LANRQDESEQ SRKRLIEQSR EFKKNTPEDL 60
RKQVAPLLKS FQGEIDALSK RSKEAEAAFL TVYKRLIDVP DPVPALDVGQ QLEIKVQRLH 120
DIETENQKLR ETLEEYNKEF AEVKNQEVTI KALKEKIREY EQTLKSQAET IALEKEQKLQ 180
NDFAEKERKL QETQMSTTSK LEEAEHKLQT LQTALEKTRT ELFDLKTKYD EETTAKADEI 240
EMIMTDLERA NQRAEVAQRE AETLREQLSS ANHSLQLASQ IQKAPDVEQA IEVLTRSSLE 300
VELAAKEREI AQLVEDVQRL QASLTKLREN SASQISQLEQ QLNAKNSTLK QLEEKLKGQA 360
DYEEVKKELN TLKSMEFAPS EGAGTQDSTK PLEVLLLEKN RSLQSENATL RISNSDLSGP 420
YSTNSISSPS PLQQSPDVNG MAPSPSQSES AGSISEGEEI DTAEIARQVK EQLIKHNIGQ 480
RIFGHYVLGL SQGSVSEILA RPKPWNKLTV RGKEPFHKMK QFLSDEQNIL ALRSIQGRQR 540
ENPGQSLNRL FQEVPKRRNG SEGNITTRIR ASETGSDEAI KSILEQAKRE LQVQKTAEPV 600
QTSSTSSSGN SDDAIRSILQ QARREMEAQQ AALDPALKPA PLSQPDLTIL TPKHLSASPM 660
STVSTYPPLA ISLKKTPAAP ETSTAALPSA PALKKEAQDV PTLDPPGSAD AAQGVLRPMK 720
SELVRGSTWK DPWWSPIQPE RRNLTSSEET KADETTASGK ERAGSSQPRA ERSQLQGPSA 780
SAEYWKEWPS AESPYSQSSE LSLTGASRSE TPQNSPLPSS PIVPMAKPAK PSVPPLTPEQ 840
YEVYMYQEVD TIELTRQVKE KLAKNGICQR IFGEKVLGLS QGSVSDMLSR PKPWSKLTQK 900
GREPFIRMQL WLNGELGQGV LPVQGQQQGP VLHSVASLQD PLQQGCVSSE STPKTSASCS 960
PAPESPMSSS ESVKSLTELV QQPCPAIETS KEGKPPEPSD PPASDSQPTT PLPLSGHSAL 1020
SIQELVAMSP ELDTYGITKR VKEVLTDNNL GQRLFGETIL GLTQGSVSDL LARPKPWHKL 1080
SLKGREPFVR MQLWLNDPNN VEKLMDMKRM EKKAYMKRRH SSVSDSQPCE PPSVGIDYSQ 1140
GASPQPQHQL KKPRVVLAPE EKEALKRAYQ QKPYPSPKTI EELATQLNLK TSTVINWFHN 1200
YRSRIRRELF IEEIQAGSQG QAGASDSPSA RSSRAAPSSE GDSCDGVEAT DAEEPGGNIV 1260
ATKSQGGLAE VAAAPADREE ATQPAEKAKA QPLCSGTPGQ DDGEDASRPR PLPEGLADAP 1320
APVPSLAAPA AGEDAATSAT APATATEAPG AARAGPAERS SALPSTSAPA NAPARRPSSL 1380
QSLFGLPEAA GARDNLVRKK KAANLNSIIH RLEKAASREE PIEWEF 1426 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0000139; C:Golgi membrane; IEA:Compara.
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003682; F:chromatin binding; IDA:MGI.
 GO:0003677; F:DNA binding; IDA:MGI.
 GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0042491; P:auditory receptor cell differentiation; IMP:MGI.
 GO:0001822; P:kidney development; IGI:MGI.
 GO:0030324; P:lung development; IMP:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0000301; P:retrograde transport, vesicle recycling within Golgi; IEA:Compara. 
Interpro
 IPR003350; Hmoeo_CUT.
 IPR017970; Homeobox_CS.
 IPR001356; Homeodomain.
 IPR009057; Homeodomain-like.
 IPR010982; Lambda_DNA-bd_dom. 
Pfam
 PF02376; CUT
 PF00046; Homeobox 
SMART
 SM00389; HOX 
PROSITE
 PS51042; CUT
 PS00027; HOMEOBOX_1
 PS50071; HOMEOBOX_2 
PRINTS