CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-009782
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative acetolactate synthase small subunit 
Protein Synonyms/Alias
 Acetohydroxy-acid synthase small subunit; AHAS; ALS 
Gene Name
 ilvH 
Gene Synonyms/Alias
 ilvN; Rv3002c; MT3082; MTV012.16c 
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
44AVGATECKDRSRMTIpupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036
Functional Description
 Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine (By similarity). 
Sequence Annotation
 DOMAIN 7 82 ACT.
 CROSSLNK 44 44 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; Isopeptide bond; Reference proteome; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 168 AA 
Protein Sequence
MSPKTHTLSV LVEDKPGVLA RVAALFSRRG FNIESLAVGA TECKDRSRMT IVVSAEDTPL 60
EQITKQLNKL INVIKIVEQD DEHSVSRELA LIKVQADAGS RSQVIEAVNL FRANVIDVSP 120
ESLTVEATGN RGKLEALLRV LEPFGIREIA QSGMVSLSRG PRGIGTAK 168 
Gene Ontology
 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0003984; F:acetolactate synthase activity; IEA:EC.
 GO:0040007; P:growth; IMP:MTBBASE.
 GO:0009097; P:isoleucine biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0009099; P:valine biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR004789; Acetalactate_synth_ssu.
 IPR019455; Acetolactate_synth_ssu_C. 
Pfam
 PF10369; ALS_ss_C 
SMART
  
PROSITE
 PS51671; ACT 
PRINTS