UniProt Accession

 VATE1_MOUSE; P50518; Q3UK59; Q8K5D6; Q99LD0 

Genbank Protein ID

 U13841; AB074758; AK146162; AK149356; AK167644; AK169854; BC003421; BC055438 

Genbank Nucleotide ID

 AAC52412.1; BAB92084.1; BAE26943.1; BAE28832.1; BAE39695.1; BAE41412.1; AAH03421.1; AAH55438.1 

Protein Name

 V-type proton ATPase subunit E 1 

Protein Synonyms/Alias

 V-ATPase subunit E 1; V-ATPase 31 kDa subunit; p31; Vacuolar proton pump subunit E 1 

Gene Name

 Atp6v1e1 

Gene Synonyms/Alias

 Atp6e; Atp6e2 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
52	LVQTQRLKIMEYYEK	ubiquitination	[1]
69	KQIEQQKKIQMSNLM	ubiquitination	[1]
99	TDLLNEAKQRLSKVV	ubiquitination	[1]
138	RMIVRCRKQDFPLVK	ubiquitination	[1]
156	QKAIPMYKIATKKDV	ubiquitination	[1]
191	YNGDRKIKVSNTLES	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 56 56 Phosphotyrosine.  

Keyword

 Acetylation; Complete proteome; Direct protein sequencing; Hydrogen ion transport; Hydrolase; Ion transport; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:UniProtKB.
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0005768; C:endosome; IDA:UniProtKB.
 GO:0005902; C:microvillus; IDA:UniProtKB.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.
 GO:0008553; F:hydrogen-exporting ATPase activity, phosphorylative mechanism; IGI:MGI.
 GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
 GO:0015991; P:ATP hydrolysis coupled proton transport; IGI:MGI. 

Interpro

 IPR002842; ATPase_V1/A1-cplx_esu. 

Pfam

 PF01991; vATP-synt_E 

SMART

  

PROSITE

  

PRINTS