CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014078
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hydroxylysine kinase 
Protein Synonyms/Alias
 5-hydroxy-L-lysine kinase; Aminoglycoside phosphotransferase domain-containing protein 1 
Gene Name
 Agphd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
36VFGFKVSKIQPLPSYubiquitination[1]
56RVHIARGKETTDDPVubiquitination[1]
105TASVCRTKGDNTISLubiquitination[1]
182ENFIWNLKNVPLLEKubiquitination[1]
189KNVPLLEKYMGALSQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Catalyzes the GTP-dependent phosphorylation of 5- hydroxy-L-lysine (By similarity). 
Sequence Annotation
 ACT_SITE 229 229 Proton acceptor (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Cytoplasm; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 376 AA 
Protein Sequence
MSSGAGWQSQ ASAKPVFTEA QASALVESVF GFKVSKIQPL PSYEDQNFRV HIARGKETTD 60
DPVEYVLKIS NTESSQTPEL IEMQNHVIMF LRAAGFPTAS VCRTKGDNTI SLISIDSGSG 120
VKSYLVRMLT YLPGRPIAEV AISHQQLYEI GRLAAQLDKA LEEFHHPKLS LFHRENFIWN 180
LKNVPLLEKY MGALSQSRNR EIVEQVIRMF KEEVMTKLSH FRECINHGDL NDHNILVDLS 240
KSASGEGVHQ VSGILDFGDM SYGYYVFEVA IVIMYMMIES TNPIQVGGHI LAGFESVIPL 300
TAVERQALFL LVCSRFSQSL VMAAYSCQLY PENKEYLMIT AKTGWKHLQQ LFDMGQKAVE 360
EIWFETAKSY ESEISM 376 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0047992; F:hydroxylysine kinase activity; IEA:EC. 
Interpro
 IPR002575; Aminoglycoside_PTrfase.
 IPR011009; Kinase-like_dom. 
Pfam
 PF01636; APH 
SMART
  
PROSITE
  
PRINTS