CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029914
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 60S ribosomal protein L26 
Protein Synonyms/Alias
  
Gene Name
 Rpl26 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
2******MKFNPFVTSacetylation[1]
36IMSSPLSKELRQKYNacetylation[1, 2]
36IMSSPLSKELRQKYNsuccinylation[2]
36IMSSPLSKELRQKYNubiquitination[3]
41LSKELRQKYNVRSMPacetylation[4]
69YKGQQIGKVVQVYRKacetylation[1]
69YKGQQIGKVVQVYRKubiquitination[3]
76KVVQVYRKKYVIYIEacetylation[1]
77VVQVYRKKYVIYIERacetylation[1, 5]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [4] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [5] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 103 AA 
Protein Sequence
MKFNPFVTSD RSKNRKRHFN APSHIRRKIM SSPLSKELRQ KYNVRSMPIR KDDEVQVVRG 60
HYKGQQIGKV VQVYRKKYVI YIERVQREKA NGTTVHVGIH PSK 103 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; IEA:Compara.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0042273; P:ribosomal large subunit biogenesis; IEA:Compara.
 GO:0006364; P:rRNA processing; IEA:Compara.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR005824; KOW.
 IPR014722; Rib_L2_dom2.
 IPR005825; Ribosomal_L24/26_CS.
 IPR005756; Ribosomal_L26/L24P_euk/arc.
 IPR008991; Translation_prot_SH3-like. 
Pfam
 PF00467; KOW 
SMART
 SM00739; KOW 
PROSITE
 PS01108; RIBOSOMAL_L24 
PRINTS