| Tag | Content |
|---|
| CPLM ID | CPLM-013435 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Outer membrane protein B |
Protein Synonyms/Alias | 168 kDa surface-layer protein; Cell surface antigen 5; Sca5; Surface protein antigen; rOmp B; rOmpB; 120 kDa surface-exposed protein; 120 kDa outer membrane protein OmpB; Surface protein antigen; p120; 32 kDa beta peptide |
Gene Name | ompB |
Gene Synonyms/Alias | spa; spaP; RP704 |
Created Date | July 27, 2013 |
Organism | Rickettsia prowazekii (strain Madrid E) |
NCBI Taxa ID | 272947 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 120 | TNIAQQAKFFNFTVA | methylation | [1] | | 130 | NFTVAAGKILNITGQ | methylation | [1] | | 156 | NAQNALTKVHGGAAI | methylation | [1] | | 204 | LTLGANSKIVNGGNG | methylation | [1] | | 231 | DNTFAGIKTINIDDC | methylation | [1] |
|
Reference | [1] Using LC-MS with de novo software to fully characterize the multiple methylations of lysine residues in a recombinant fragment of an outer membrane protein from a virulent strain of Rickettsia prowazekii. Chao CC, Wu SL, Ching WM. Biochim Biophys Acta. 2004 Nov 1;1702(2):145-52. [ PMID: 15488766] |
Functional Description | The 120 kDa surface-exposed protein is a major structural protein which may play a role as a rickettsial virulence factor and/or immunogen during infection. |
Sequence Annotation | DOMAIN 1355 1643 Autotransporter. |
Keyword | Cell membrane; Cell outer membrane; Complete proteome; Direct protein sequencing; Membrane; Periplasm; Reference proteome; Secreted; Transmembrane; Transmembrane beta strand; Virulence. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1643 AA |
Protein Sequence | MAQKPNFLKK IISAGLVTAS TATIVAGFSG VAMGAAMQYN RTTNAAATTF DGIGFDQAAG 60
ANIPVAPNSV ITANANNPIT FNTPNGHLNS LFLDTANDLA VTINEDTTLG FITNIAQQAK 120
FFNFTVAAGK ILNITGQGIT VQEASNTINA QNALTKVHGG AAINANDLSG LGSITFAAAP 180
SVLEFNLINP TTQEAPLTLG ANSKIVNGGN GTLNITNGFI QVSDNTFAGI KTINIDDCQG 240
LMFNSTPDAA NTLNLQVGGN TINFNGIDGT GKLVLVSKNG AATEFNVTGT LGGNLKGIIE 300
LNTAAVAGKL ISQGGAANAV IGTDNGAGRA AGFIVSVDNG NAATISGQVY AKNMVIQSAN 360
AGGQVTFEHI VDVGLGGTTN FKTADSKVII TENSNFGSTN FGNLDTQIVV PDTKILKGNF 420
IGDVKNNGNT AGVITFNANG ALVSASTDPN IAVTNINAIE AEGAGVVELS GIHIAELRLG 480
NGGSIFKLAD GTVINGPVNQ NALMNNNALA AGSIQLDGSA IITGDIGNGG VNAALQHITL 540
ANDASKILAL DGANIIGANV GGAIHFQANG GTIKLTNTQN NIVVNFDLDI TTDKTGVVDA 600
SSLTNNQTLT INGSIGTVVA NTKTLAQLNI GSSKTILNAG DVAINELVIE NNGSVQLNHN 660
TYLITKTINA ANQGQIIVAA DPLNTNTTLA DGTNLGSAEN PLSTIHFATK AANADSILNV 720
GKGVNLYANN ITTNDANVGS LHFRSGGTSI VSGTVGGQQG HKLNNLILDN GTTVKFLGDT 780
TFNGGTKIEG KSILQISNNY TTDHVESADN TGTLEFVNTD PITVTLNKQG AYFGVLKQVI 840
ISGPGNIVFN EIGNVGIVHG IAANSISFEN ASLGTSLFLP SGTPLDVLTI KSTVGNGTVD 900
NFNAPIVVVS GIDSMINNGQ IIGDKKNIIA LSLGSDNSIT VNANTLYSGI RTTKNNQGTV 960
TLSGGMPNNP GTIYGLGLEN GSPKLKQVTF TTDYNNLGSI IANNVTINDY VTLTTGGIAG 1020
TDFDAKITLG SVNGNANVRF VDSTFSDPRS MIVATQANKG TVTYLGNALV SNIGSLDTPV 1080
ASVRFTGNDS GAGLQGNIYS QNIDFGTYNL TILNSNVILG GGTTAINGEI DLLTNNLIFA 1140
NGTSTWGDNT SISTTLNVSS GNIGQVVIAE DAQVNATTTG TTTIKIQDNA NANFSGTQAY 1200
TLIQGGARFN GTLGAPNFAV TGSNIFVKYE LIRDSNQDYV LTRTNDVLNV VTTAVGNSAI 1260
ANAPGVSQNI SRCLESTNTA AYNNMLLAKD PSDVATFVGA IATDTSAAVT TVNLNDTQKT 1320
QDLLSNRLGT LRYLSNAETS DVAGSATGAV SSGDEAEVSY GVWAKPFYNI AEQDKKGGIA 1380
GYKAKTTGVV VGLDTLASDN LMIGAAIGIT KTDIKHQDYK KGDKTDINGL SFSLYGSQQL 1440
VKNFFAQGNA IFTLNKVKSK SQRYFFESNG KMSKQIAAGN YDNMTFGGNL IFGYDYNAMP 1500
NVLVTPMAGL SYLKSSNENY KETGTTVANK RINSKFSDRV DLIVGAKVAG STVNITDIVI 1560
YPEIHSFVVH KVNGKLSNSQ SMLDGQTAPF ISQPDRTAKT SYNIGLSANI KSDAKMEYGI 1620
GYDFNSASKY TAHQGTLKVR VNF 1643 |
Gene Ontology | GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell. GO:0009986; C:cell surface; IEA:UniProtKB-SubCell. GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell. GO:0005886; C:plasma membrane; IEA:UniProtKB-KW. GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |