CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036262
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Deoxycytidine kinase 
Protein Synonyms/Alias
  
Gene Name
 DCK 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
117ASLNGKLKDAEKPVLubiquitination[1]
211YLEKLHYKHESWLLHubiquitination[2]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 317 AA 
Protein Sequence
MATPPKRSCP SFSASSEGTR IKKISIEGNI AAGKSTFVNI LKQLCEDWEV VPEPVARWCN 60
VQSTQDEFEE LTMSQKNGGN VLQMMYEKPE RWSFTFQTYA CLSRIRAQLA SLNGKLKDAE 120
KPVLFFERSV YSDRYIFASN LYESECMNET EWTIYQDWHD WMNNQFGQSL ELDGIIYLQA 180
TPETCLHRIY LRGRNEEQGI PLEYLEKLHY KHESWLLHRT LKTNFDYLQE VPILTLDVNE 240
DFKDKYESLV EKSCSVAQAG VQWHNLGSLP SPPPRFNQFC LSLLSQRVFE YFVILLKTTG 300
SQMVPDTSAL CIFVTSY 317 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
 GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. 
Interpro
 IPR002624; Deoxynucleoside_kinase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF01712; dNK 
SMART
  
PROSITE
  
PRINTS