CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038340
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein transport protein Sec23A 
Protein Synonyms/Alias
  
Gene Name
 Sec23a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
81CQVDYRAKLWACNFCacetylation[1]
156LGCEGISKSYVFRGTacetylation[1]
169GTKDLSAKQLQEMLGubiquitination[2]
179QEMLGLSKVPVTQATubiquitination[2]
278MVVGDELKTPIRSWHubiquitination[2]
289RSWHDIEKDNAKYVKubiquitination[2]
300KYVKKGTKHFEALANacetylation[1]
363TFQRVFTKDIHGQFKacetylation[1]
363TFQRVFTKDIHGQFKubiquitination[2]
527QLIRLCQKFGEYHKDubiquitination[2]
640ETIAQWRKSGYQDMPubiquitination[2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 736 AA 
Protein Sequence
MTTYLEFIQQ NEERDGVRFS WNVWPSSRLE ATRMVVPVAA LFTPLKERPD LPPIQYEPVL 60
CSRTTCRAVL NPLCQVDYRA KLWACNFCYQ RNQRGPQMPL IFLYVVDTCI EDEDLQALKE 120
SMQMSLSLLP PTALVGLITF GRMVQVHELG CEGISKSYVF RGTKDLSAKQ LQEMLGLSKV 180
PVTQATRGPQ VQQPPPSNRF LQPVQKIDMN LTDLLGELQR DPWPVPQGKR PLRSSGVALS 240
IAVGLLECTF PNTGARIMMF IGGPATQGPG MVVGDELKTP IRSWHDIEKD NAKYVKKGTK 300
HFEALANRAA TTGHVIDIYA CALDQTGLLE MKCCPNLTGG YMVMGDSFNT SLFKQTFQRV 360
FTKDIHGQFK MGFGGTLEIK TSREIKISGA IGPCVSLNSK GPCVSENEIG TGGTCQWKIC 420
GLSPTTTLAI YFEVVNQHNA PIPQGGRGAV QFVTQYQHSS GQRRIRVTTI ARNWADAQTQ 480
IQNIAASFDQ EAAAILMARL AIYRAETEEG PDVLRWLDRQ LIRLCQKFGE YHKDDPNSFR 540
FSETFSLYPQ FMFHLRRSPF LQVFNNSPDE SSYYRHHFMR QDLTQSLIMI QPILYAYSFS 600
GPPEPVLLDS SSILADRILL MDTFFQILIY HGETIAQWRK SGYQDMPEYE NFRHLLQAPV 660
DDAQEILHSR FPMPRYIDTE HGGSQARFLL SKVNPSQTHN NMYAWGQESG APILTDDVSL 720
QVFMDHLKKL AVSSAA 736 
Gene Ontology
 GO:0030127; C:COPII vesicle coat; IEA:InterPro.
 GO:0000139; C:Golgi membrane; IDA:MGI.
 GO:0048471; C:perinuclear region of cytoplasm; IDA:MGI.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006888; P:ER to Golgi vesicle-mediated transport; IEA:InterPro.
 GO:0006886; P:intracellular protein transport; TAS:MGI. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR006900; Sec23/24_helical_dom.
 IPR006896; Sec23/24_trunk_dom.
 IPR012990; Sec23_24_beta_S.
 IPR002035; VWF_A.
 IPR006895; Znf_Sec23_Sec24. 
Pfam
 PF00626; Gelsolin
 PF08033; Sec23_BS
 PF04815; Sec23_helical
 PF04811; Sec23_trunk
 PF04810; zf-Sec23_Sec24 
SMART
  
PROSITE
  
PRINTS