UniProt Accession

 IAH1_HUMAN; Q2TAA2 

Genbank Protein ID

 AK291984; CH471053; BC111025 

Genbank Nucleotide ID

 BAF84673.1; EAX00983.1; AAI11026.1 

Protein Name

 Isoamyl acetate-hydrolyzing esterase 1 homolog 

Protein Synonyms/Alias

  

Gene Name

 IAH1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
219	LWPLIEKKVSSLPLL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Probable lipase (By similarity). 

Sequence Annotation

 ACT_SITE 24 24 Nucleophile (By similarity).
 ACT_SITE 196 196 By similarity.
 ACT_SITE 199 199 By similarity.
 BINDING 56 56 Substrate; via amide nitrogen (By
 BINDING 89 89 Substrate (By similarity).  

Keyword

 Complete proteome; Hydrolase; Lipid degradation; Lipid metabolism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 248 AA 

Protein Sequence

Gene Ontology

 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. 

Interpro

 IPR001087; Lipase_GDSL.
 IPR013831; SGNH_hydro-type_esterase_dom. 

Pfam

 PF00657; Lipase_GDSL 

SMART

  

PROSITE

 PS01098; LIPASE_GDSL_SER 

PRINTS