CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012906
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Actin-depolymerizing factor 2 
Protein Synonyms/Alias
 ADF-2; AtADF2 
Gene Name
 ADF2 
Gene Synonyms/Alias
 At3g46000; F16L2_210 
Created Date
 July 27, 2013 
Organism
 Arabidopsis thaliana (Mouse-ear cress) 
NCBI Taxa ID
 3702 
Lysine Modification
Position
Peptide
Type
References
133EMGLDVFKSRTN***acetylation[1]
Reference
 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031
Functional Description
 Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (By similarity). 
Sequence Annotation
 DOMAIN 5 137 ADF-H.  
Keyword
 Actin-binding; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 137 AA 
Protein Sequence
MANAASGMAV HDDCKLKFME LKAKRTFRTI VYKIEDKQVI VEKLGEPEQS YDDFAASLPA 60
DDCRYCIYDF DFVTAENCQK SKIFFIAWSP DTAKVRDKMI YASSKDRFKR ELDGIQVELQ 120
ATDPTEMGLD VFKSRTN 137 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; IEA:InterPro.
 GO:0005737; C:cytoplasm; IDA:TAIR.
 GO:0005634; C:nucleus; IDA:TAIR.
 GO:0005886; C:plasma membrane; IDA:TAIR.
 GO:0030042; P:actin filament depolymerization; IEA:InterPro. 
Interpro
 IPR002108; Actin-bd_cofilin/tropomyosin.
 IPR017904; ADF/Cofilin/Destrin. 
Pfam
 PF00241; Cofilin_ADF 
SMART
 SM00102; ADF 
PROSITE
 PS51263; ADF_H 
PRINTS