CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001711
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable elongation factor 1-beta 
Protein Synonyms/Alias
 EF-1-beta 
Gene Name
 Ef1beta 
Gene Synonyms/Alias
 CG6341 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
130YAAKKSKKPALIAKSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
 EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. 
Sequence Annotation
 MOD_RES 104 104 Phosphoserine.  
Keyword
 Complete proteome; Elongation factor; Phosphoprotein; Protein biosynthesis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 222 AA 
Protein Sequence
MAFGDVTTPQ GLKELNAFLA DNSYISGYTP SKADLSVFDA LGKAPSADNV NVARWYRHIA 60
SFEAAERAAW SGTPLPQLAG GKPTVAAAAK PAADDDDDVD LFGSDDEEDE EAERIKQERV 120
AAYAAKKSKK PALIAKSSVL LDVKPWDDET DMKEMENNVR TIEMDGLLWG ASKLVPVGYG 180
INKLQIMCVI EDDKVSIDLL QEKIEEFEDF VQSVDIAAFN KI 222 
Gene Ontology
 GO:0005829; C:cytosol; NAS:FlyBase.
 GO:0005853; C:eukaryotic translation elongation factor 1 complex; ISS:FlyBase.
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0003746; F:translation elongation factor activity; ISS:FlyBase. 
Interpro
 IPR018940; EF-1_beta_acid_region_euk.
 IPR010987; Glutathione-S-Trfase_C-like.
 IPR014717; Transl_elong_EF1B/ribosomal_S6.
 IPR001326; Transl_elong_EF1B_B/D_CS.
 IPR014038; Transl_elong_fac_EF1B_bsu/dsu. 
Pfam
 PF10587; EF-1_beta_acid
 PF00736; EF1_GNE 
SMART
 SM00888; EF1_GNE 
PROSITE
 PS00824; EF1BD_1
 PS00825; EF1BD_2 
PRINTS