CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027217
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 L-lactate dehydrogenase 
Protein Synonyms/Alias
  
Gene Name
 Ldhal6b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
205WKLSGFPKNRIIGSGubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Glycolysis; NAD; Oxidoreductase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 382 AA 
Protein Sequence
MAWATSILRA SRRVSTTRVD FKGFGIALWP SQVQRVPPNR AWWSLTPTSS MATVKGELIQ 60
HISSEEPVLH NKVSIVGTGS VGMACAIGII AKGLTDELAL VDNNEEKMKG ETMDLQHGSV 120
FMKMPNIVCS KDFRVTANSE VVIITAGARQ EKNETRLNLV QRNVTIFKAM VAEIIKHSPR 180
CKIIVVSNPV DILTFVTWKL SGFPKNRIIG SGCNLDTARF RYMLGQRLGI HSESCHGWVL 240
GEHGDSSVPV WSGVNIAGVP LRELNSAIGT SKDPEKWGDV HKEVIASAYN IIKMKGYTSW 300
AIGLSVTDIA ESILKNLRKT HPVTTKIQGL YGIKEEVFLS VPCILGESGI SDIIKVKLSP 360
TEEAQMVKSA ETIWKIQKDI KF 382 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0004459; F:L-lactate dehydrogenase activity; IEA:EC.
 GO:0044262; P:cellular carbohydrate metabolic process; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:UniProtKB-KW. 
Interpro
 IPR001557; L-lactate/malate_DH.
 IPR011304; L-lactate_DH.
 IPR018177; L-lactate_DH_AS.
 IPR022383; Lactate/malate_DH_C.
 IPR001236; Lactate/malate_DH_N.
 IPR015955; Lactate_DH/Glyco_Ohase_4_C.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF02866; Ldh_1_C
 PF00056; Ldh_1_N 
SMART
  
PROSITE
 PS00064; L_LDH 
PRINTS
 PR00086; LLDHDRGNASE.