UniProt Accession

 LAC2_HUMAN; P0CG05; A0M8Q4; P80423 

Genbank Protein ID

 J00253; X51754; X51755; D87017; D87023; D87023; CH471095; CH471095 

Genbank Nucleotide ID

 AAA59107.1; CAB38569.1; CAA36049.1; BAA20015.1; BAA20026.1; BAA20028.1; EAW59547.1; EAW59549.1 

Protein Name

 Ig lambda-2 chain C regions 

Protein Synonyms/Alias

  

Gene Name

 IGLC2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
50	KADSSPVKAGVETTT	ubiquitination	[1]
60	VETTTPSKQSNNKYA	ubiquitination	[1]
65	PSKQSNNKYAASSYL	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

 DOMAIN 7 101 Ig-like.
 DISULFID 28 87
 DISULFID 105 105 Interchain (with heavy chain).  

Keyword

 3D-structure; Bence-Jones protein; Complete proteome; Direct protein sequencing; Disulfide bond; Immunoglobulin C region; Immunoglobulin domain; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 106 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; TAS:Reactome.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0003823; F:antigen binding; IEA:UniProtKB-KW.
 GO:0006958; P:complement activation, classical pathway; TAS:Reactome.
 GO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome.
 GO:0045087; P:innate immune response; TAS:Reactome. 

Interpro

 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set. 

Pfam

 PF07654; C1-set 

SMART

 SM00407; IGc1 

PROSITE

 PS50835; IG_LIKE
 PS00290; IG_MHC 

PRINTS