CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-044287
UniProt Accession
I7HPW1_MOUSE
;
I7HPW1
Genbank Protein ID
CR974462
Genbank Nucleotide ID
CAM17899.1
Protein Name
Bromodomain containing 2
Protein Synonyms/Alias
Bromodomain-containing protein 2
Gene Name
Brd2
Gene Synonyms/Alias
RP23-222K15.1-004
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
30
PEAAAPG
K
RIRKPSL
acetylation
[1]
Reference
[1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
PLoS One. 2012;7(12):e50545. [
PMID: 23236377
]
Functional Description
Sequence Annotation
Keyword
Bromodomain; Complete proteome; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
473 AA
Protein Sequence
MLQNVTPHKL PGEGNAGLLG LGPEAAAPGK RIRKPSLLYE GFESPTMASV PALQLAPANP 60
PPPEVSNPKK PGRVTNQLQY LHKVVMKALW KHQFAWPFRQ PVDAVKLGLP DYHKIIKQPM 120
DMGTIKRRLE NNYYWAASEC MQDFNTMFTN CYIYNKPTDD IVLMAQTLEK IFLQKVASMP 180
QEEQELVVTI PKNSHKKGAK LAALQGSITS AHQVPAVSSV SHTALYTPPP EIPTTVLNIP 240
HPSVISSPLL KSLHSAGPPL LAVSAAPPAQ PLAKKKGVKR KADTTTPTPT AILAPGSPAS 300
PPGSLEPKAA RLPPMRRESG RPIKPPRKDL PDSQQQHQSS KKGKLSEQLK HCNGILKELL 360
SKKHAAYAWP FYKPVDASAL GLHDYHDIIK HPMDLSTVKR KMENRDYRDA QEFAADVRLM 420
FSNCYKYNPP DHDVVAMARK LQDVFEFRYA KMPDEPLEPG PLPVSTALPP GLT 473
Gene Ontology
GO:0005737
; C:cytoplasm; IDA:MGI.
GO:0005634
; C:nucleus; IDA:MGI.
GO:0003682
; F:chromatin binding; IEA:Compara.
GO:0006334
; P:nucleosome assembly; IEA:Compara.
GO:0006357
; P:regulation of transcription from RNA polymerase II promoter; IEA:Compara.
Interpro
IPR001487
; Bromodomain.
IPR018359
; Bromodomain_CS.
Pfam
PF00439
; Bromodomain
SMART
SM00297
; BROMO
PROSITE
PS00633
; BROMODOMAIN_1
PS50014
; BROMODOMAIN_2
PRINTS
PR00503
; BROMODOMAIN.