CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039780
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 C2 domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 C2CD3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
86DALQTEPKAVRTTTRubiquitination[1, 2]
279LKGRAPRKQMSLLNSubiquitination[1]
298PQIRTVAKSHSDSCIubiquitination[1]
326ALLEQGNKLRNAMVIubiquitination[1, 2, 3]
373AFSRNRFKDHIEDHLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MKQRKGQGSG GSRGRKKRGL SDISPSTSLP PLVEGQLRCF LKLTVNRVIW KIAKPPTCVL 60
VRVRWWGETS DGTLFCPRDA LQTEPKAVRT TTRYAIRCGP KQFTSYLTDM AVLVLEVITK 120
LDGLPIGRVQ INGLAQLSPT HQINGFFTIV SSTSKKLGEL QVSLALEPLS ETYDSYHPLP 180
TTDMTENVLL SKQGFRENTE PSSTQFQVPS RPRDIHTIKI DGKELAANSS RSTTPRGKDH 240
VCFAENPDTI KDSSFGLQHS LNSGQSLESV TLKGRAPRKQ MSLLNSSEFQ PQIRTVAKSH 300
SDSCILSSNN LPTKDLLSAL LEQGNKLRNA MVISAMKSSP ETSMLLDQVH PPINEDSLRA 360
STQIRAFSRN RFKDHIEDHL LPSTENTFWR HDTKADTRAI QLLLGSLGLT RCRDCRRSLV 420
HAVLNGAQAG VQWRDIGSLQ PPPPSRLPWP PKVPRLQPLP GRHPVWEVRS VSAWPPIVWD 480
VRIPSAWLPS LESEERLCPP AIPSRK 506 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS