CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015537
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 UDP-glucuronosyltransferase 1-7C 
Protein Synonyms/Alias
 UDPGT 1-7C; UGT1*7C; UGT1-07C; UGT1.7C; UDP-glucuronosyltransferase 1A7C; UGT1A10 
Gene Name
 Ugt1a7c 
Gene Synonyms/Alias
 Ugt1a10 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
316VSEIPEKKAMEIAEAubiquitination[1]
345TRPSNLAKNTILVKWubiquitination[1]
351AKNTILVKWLPQNDLubiquitination[1]
363NDLLGHPKTRAFITHubiquitination[1]
432LKTVINNKSYKENIMubiquitination[1]
435VINNKSYKENIMRLSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. 
Sequence Annotation
 CARBOHYD 293 293 N-linked (GlcNAc...) (Potential).
 CARBOHYD 431 431 N-linked (GlcNAc...) (Potential).  
Keyword
 Alternative splicing; Complete proteome; Endoplasmic reticulum; Glycoprotein; Glycosyltransferase; Membrane; Microsome; Reference proteome; Signal; Transferase; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 531 AA 
Protein Sequence
MAPADFPASL PLCVCLLLAS GLAQAGRLLV VPMDGSHWFT MQTVVEKLLH KGHEVVVVVP 60
EVSWQLTKPL NFVVKTYAVS HTQEDLNREF KIFIDAQWKS QQEGGILPLL DSPAKGFFEL 120
LFSHCRSLFN DKKLVEYLKQ TSFDAVFLDP FDVCGLTVAK YFSLPSVVFS RGIFCHYLED 180
AAQCPSPPSY IPRMLLKFTD TMTFKERTRN LLAYMGERAF CHKFFKSAAD IASEVLQTPV 240
TMTDLFSPVS IWLLRTDFVL EFPRPVMPNV IYIGGINCHQ GKPLSKEFEA YVNASGEHGI 300
VVFSLGSMVS EIPEKKAMEI AEALGRIPQT VLWRYTGTRP SNLAKNTILV KWLPQNDLLG 360
HPKTRAFITH SGSHGIYEGI CNGVPMVMMP LFGDQMDNAK RMETRGAGVT LNVLEMTADD 420
LENALKTVIN NKSYKENIMR LSSLHKDRPI EPLDLAVFWV EYVMRHKGAP HLRPAAHDLT 480
WYQYHSLDVI GFLLAIVLTV VFIVFKCCAY GCRKCFGGKG RVKKSHKSKT H 531 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0015020; F:glucuronosyltransferase activity; IEA:EC. 
Interpro
 IPR002213; UDP_glucos_trans. 
Pfam
 PF00201; UDPGT 
SMART
  
PROSITE
 PS00375; UDPGT 
PRINTS