CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-000139
UniProt Accession
Y1013_MYCTU
;
O05598
;
L0T866
Genbank Protein ID
AL123456
Genbank Nucleotide ID
CCP43763.1
Protein Name
Putative ligase Rv1013
Protein Synonyms/Alias
Gene Name
pks16
Gene Synonyms/Alias
Rv1013
Created Date
July 27, 2013
Organism
Mycobacterium tuberculosis
NCBI Taxa ID
1773
Lysine Modification
Position
Peptide
Type
References
528
LGPGTIP
K
TPSGKLR
pupylation
[1]
Reference
[1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
PLoS One. 2010 Jan 6;5(1):e8589. [
PMID: 20066036
]
Functional Description
Sequence Annotation
CROSSLNK 528 528 Isoglutamyl lysine isopeptide (Lys-Gln)
Keyword
Complete proteome; Isopeptide bond; Ligase; Reference proteome; Ubl conjugation.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
544 AA
Protein Sequence
MSRFTEKMFH NARTATTGMV TGEPHMPVRH TWGEVHERAR CIAGGLAAAG VGLGDVVGVL 60
AGFPVEIAPT AQALWMRGAS LTMLHQPTPR TDLAVWAEDT MTVIGMIEAK AVIVSEPFLV 120
AIPILEQKGM QVLTVADLLA SDPIGPIEVG EDDLALMQLT SGSTGSPKAV QITHRNIYSN 180
AEAMFVGAQY DVDKDVMVSW LPCFHDMGMV GFLTIPMFFG AELVKVTPMD FLRDTLLWAK 240
LIDKYQGTMT AAPNFAYALL AKRLRRQAKP GDFDLSTLRF ALSGAEPVEP ADVEDLLDAG 300
KPFGLRPSAI LPAYGMAETT LAVSFSECNA GLVVDEVDAD LLAALRRAVP ATKGNTRRLA 360
TLGPLLQDLE ARIIDEQGDV MPARGVGVIE LRGESLTPGY LTMGGFIPAQ DEHGWYDTGD 420
LGYLTEEGHV VVCGRVKDVI IMAGRNIYPT DIERAAGRVD GVRPGCAVAV RLDAGHSRES 480
FAVAVESNAF EDPAEVRRIE HQVAHEVVAE VDVRPRNVVV LGPGTIPKTP SGKLRRANSV 540
TLVT 544
Gene Ontology
GO:0005618
; C:cell wall; IDA:MTBBASE.
GO:0005886
; C:plasma membrane; IDA:MTBBASE.
GO:0016874
; F:ligase activity; IEA:UniProtKB-KW.
Interpro
IPR020845
; AMP-binding_CS.
IPR000873
; AMP-dep_Synth/Lig.
Pfam
PF00501
; AMP-binding
SMART
PROSITE
PS00455
; AMP_BINDING
PRINTS