CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015150
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 529 
Protein Synonyms/Alias
  
Gene Name
 ZNF529 
Gene Synonyms/Alias
 KIAA1615 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
153SENVPSYKTHESLTLubiquitination[1, 2]
197QKIHTGGKNYECNQCubiquitination[1]
268RTFERVGKVTPLQRVubiquitination[1]
289FECSFCGKSFRVHAQubiquitination[1]
560PKIYTGEKSFD****ubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 39 119 KRAB.
 ZN_FING 199 221 C2H2-type 1; degenerate.
 ZN_FING 254 276 C2H2-type 2; degenerate.
 ZN_FING 282 304 C2H2-type 3.
 ZN_FING 310 332 C2H2-type 4.
 ZN_FING 338 360 C2H2-type 5.
 ZN_FING 366 388 C2H2-type 6.
 ZN_FING 394 416 C2H2-type 7.
 ZN_FING 422 444 C2H2-type 8.
 ZN_FING 450 472 C2H2-type 9.
 ZN_FING 478 500 C2H2-type 10.
 ZN_FING 506 528 C2H2-type 11.
 ZN_FING 534 556 C2H2-type 12; degenerate.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 563 AA 
Protein Sequence
MANSSFIGDH VHGAPHAVMP EVEFPDQFFT VLTMDHELVT LRDVVINFSQ EEWEYLDSAQ 60
RNLYWDVMME NYSNLLSLDL ESRNETKHLS VGKDIIQNTG SQWEVMESSK LCGLEGSIFR 120
NDWQSKSKID LQGPEVGYFS QMKIISENVP SYKTHESLTL PRRTHDSEKP YEYKEYEKVF 180
SCDLEFDEYQ KIHTGGKNYE CNQCWKTFGI DNSSMLQLNI HTGVKPCKYM EYGNTCSFYK 240
DFNVYQKIHN EKFYKCKEYR RTFERVGKVT PLQRVHDGEK HFECSFCGKS FRVHAQLTRH 300
QKIHTDEKTY KCMECGKDFR FHSQLTEHQR IHTGEKPYKC MHCEKVFRIS SQLIEHQRIH 360
TGEKPYACKE CGKAFGVCRE LARHQRIHTG KKPYECKACG KVFRNSSSLT RHQRIHTGEK 420
PYKCKECEKA FGVGSELTRH ERIHSGQKPY ECKECGKFFR LTSALIQHQR IHSGEKPYEC 480
KVCGKAFRHS SALTEHQRIH TGEKPYECKA CGKAFRHSSS FTKHQRIHTD DKPYECKECG 540
NSFSVVGHLT CQPKIYTGEK SFD 563 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS