UniProt Accession

 PPNK_MYCPN; P75508 

Genbank Protein ID

 U00089 

Genbank Nucleotide ID

 AAB96214.1 

Protein Name

 Probable inorganic polyphosphate/ATP-NAD kinase 

Protein Synonyms/Alias

 Poly(P)/ATP NAD kinase 

Gene Name

 ppnK 

Gene Synonyms/Alias

 MPN_267; MP566 

Created Date

 July 27, 2013 

Organism

 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 

NCBI Taxa ID

 272634 

Lysine Modification

Position	Peptide	Type	References
200	TQVEFVVKKAFNPQQ	acetylation	[1]
201	QVEFVVKKAFNPQQF	acetylation	[1]
257	KLKSTFIKQS*****	acetylation	[1]

Reference

 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 

Functional Description

 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity). 

Sequence Annotation

  

Keyword

 ATP-binding; Complete proteome; Cytoplasm; Kinase; NAD; NADP; Nucleotide-binding; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 259 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:HAMAP.
 GO:0003951; F:NAD+ kinase activity; IEA:HAMAP.
 GO:0019674; P:NAD metabolic process; IEA:InterPro.
 GO:0006741; P:NADP biosynthetic process; IEA:InterPro. 

Interpro

 IPR017438; ATP-NAD_kinase_dom_1.
 IPR016064; ATP-NAD_kinase_PpnK-typ.
 IPR017437; ATP-NAD_kinase_PpnK-typ_all-b.
 IPR002504; PolyP/ATP_NADK_prd. 

Pfam

 PF01513; NAD_kinase 

SMART

  

PROSITE

  

PRINTS