| Tag | Content |
|---|
| CPLM ID | CPLM-022353 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc finger protein 586 |
Protein Synonyms/Alias | |
Gene Name | ZNF586 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 251 | AENSSLIKHLRVHTG | ubiquitination | [1] |
|
Reference | [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C. Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [ PMID: 21890473] |
Functional Description | May be involved in transcriptional regulation. |
Sequence Annotation | DOMAIN 15 87 KRAB.
ZN_FING 88 116 C2H2-type 1; degenerate.
ZN_FING 122 144 C2H2-type 2; degenerate.
ZN_FING 150 172 C2H2-type 3; degenerate.
ZN_FING 178 200 C2H2-type 4.
ZN_FING 206 228 C2H2-type 5.
ZN_FING 234 256 C2H2-type 6.
ZN_FING 262 284 C2H2-type 7.
ZN_FING 290 312 C2H2-type 8.
ZN_FING 317 339 C2H2-type 9.
ZN_FING 345 367 C2H2-type 10.
ZN_FING 373 395 C2H2-type 11. |
Keyword | Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 402 AA |
Protein Sequence | MAAAAALRAP AQSSVTFEDV AVNFSLEEWS LLNEAQRCLY RDVMLETLTL ISSLGCWHGG 60
EDEAAPSKQS TCIHIYKDQG GHSGERPYEC GEYRKLFKNK SCLTEPRRDH KHRNVRTGER 120
PYECSKYGKL FHQKPTLHIH ERFHTGQKTY ECSECGKSFH QSSSLLQRQT LHTRERPYEC 180
IECGKAFAEK SSLINHRKVH SGAKRYECNE CGKSFAYTSS LIKHRRIHTG ERPYECSECG 240
RSFAENSSLI KHLRVHTGER PYECVECGKS FRRSSSLLQH QRVHTRERPY ECSECGKSFS 300
LRSNLIHHQR VHTGERHECG QCGKSFSRKS SLIIHLRVHT GERPYECSDC GKSFAENSSL 360
IKHLRVHTGE RPYECIDCGK SFRHSSSFRR HQRVHTGMRP YK 402 |
Gene Ontology | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0008270; F:zinc ion binding; IEA:InterPro. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |